Dhingra, Vandana (2014) Genetics of premenstrual syndrome: investigation of specific serotonin receptor polymorphisms. Doctoral thesis, Keele University.

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Abstract

Premenstrual dysphoric disorder (PMDD) is a distressing and disabling syndrome causing a significant degree of impairment on daily functioning and interpersonal relationships in 3-8% of the women. With the convincing evidence that PMS is inheritable and that serotonin is important in the pathogenesis of PMS, and failure of initial studies to demonstrate significant associations between key genes controlling the synthesis, reuptake and catabolism of serotonin and PMDD, the main aim of this thesis was to target the functional polymorphisms of serotonin receptors.

Item Type: Thesis (Doctoral)
Subjects: Q Science > QH Natural history > QH426 Genetics
Divisions: Faculty of Medicine and Health Sciences > Institute for Science and Technology in Medicine
Depositing User: Michael Debenham
Date Deposited: 24 Nov 2015 12:38
Last Modified: 24 Nov 2015 12:38
URI: http://eprints.keele.ac.uk/id/eprint/1213

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