Chen, Y, Dawes, PT, Packham, JC and Mattey, DL (2012) Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study. Arthritis Research & Therapy, 14 (2). R81 -?.

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Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study..pdf - Published Version
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Abstract

Transforming growth factor-beta1 (TGF-beta1) is a pleiotropic cytokine that plays important roles in immunity and inflammation. Some studies have suggested that polymorphism in the TGFB1 gene is associated with heart disease in the general population. The purpose of the present study was to determine whether common single-nucleotide polymorphisms (SNP) in the TGFB1 gene are associated with ischaemic heart disease (IHD) and/or myocardial infarction (MI) in patients with rheumatoid arthritis (RA), and to investigate the influence of smoking on any association.

Item Type: Article
Additional Information: This is the final published version of the article (version of record). It first appeared online via BioMed Central at https://dx.doi.org/10.1186/ar3804 - please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: smoking, heart failure, rheumatoid arthritis
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine and Health Sciences > Institute for Science and Technology in Medicine
Related URLs:
Depositing User: Symplectic
Date Deposited: 27 Nov 2014 09:48
Last Modified: 17 Dec 2018 16:30
URI: http://eprints.keele.ac.uk/id/eprint/129

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