Roberts, S, Colombier, P, Sowman, A, Mennan, C, Rolfing, J, Guicheux, J and Edwards, J (2016) Ageing in the musculoskeletal system. Acta Orthopaedica, 87 (363). 15- 25. ISSN 1745-3682

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Abstract

The extent of ageing in the musculoskeletal system during the life course affects the quality and length of life. Loss of bone, degraded articular cartilage, and degenerate, narrowed intervertebral discs are primary features of an ageing skeleton, and together they contribute to pain and loss of mobility. This review covers the cellular constituents that make up some key components of the musculoskeletal system and summarizes discussion from the 2015 Aarhus Regenerative Orthopaedic Symposium (AROS) (Regeneration in the Ageing Population) about how each particular cell type alters within the ageing skeletal microenvironment.

Item Type: Article
Additional Information: This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Informa Healthcare at https://doi.org/10.1080/17453674.2016.1244750 Please refer to any applicable terms of use of the publisher.
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine and Health Sciences > Institute for Science and Technology in Medicine
Depositing User: Symplectic
Date Deposited: 20 Oct 2016 08:46
Last Modified: 04 Jun 2018 13:09
URI: http://eprints.keele.ac.uk/id/eprint/2295

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