O'Brien, M and Cooper, DA and Dolan, J (2017) Continuous flow iodination using an automated computer-vision controlled liquid-liquid extraction system. Tetrahedron Letters, 58 (9). 829 -834. ISSN 0040-4039

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Abstract

Abstract A dynamic computer-vision control system incorporating open-source software technologies (Python, OpenCV) was used to automate a gravity based in-line liquid-liquid extraction during the iodination of enaminones in continuous flow. The system was able to cope with significant colouration of the organic reaction stream and with significant volume/flow changes in the aqueous and organic phase streams due to extraction of the water soluble acetonitrile co-solvent.

Item Type: Article
Additional Information: This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Elsevier at http://dx.doi.org/10.1016/j.tetlet.2017.01.029 - please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: open-source, automation, computer-vision, continuous-flow, iodination
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Natural Sciences > School of Chemical and Physical Sciences
Depositing User: Symplectic
Date Deposited: 13 Feb 2017 12:42
Last Modified: 13 Feb 2017 12:42
URI: http://eprints.keele.ac.uk/id/eprint/2897

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