Peat, G ORCID: https://orcid.org/0000-0002-9008-0184, Riley, RD ORCID: https://orcid.org/0000-0001-8699-0735, Croft, P, Morley, KI, Kyzas, PA, Moons, KGM, Perel, P, Steyerberg, EW, Schroter, S, Altman, DG and Hemingway, H (2014) Improving the transparency of prognosis research: the role of reporting, data sharing, registration, and protocols. PLoS Medicine, 11 (7). e1001671 -?.

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Abstract

Prognosis research is concerned with predicting outcomes to make health care more effective. It has a crucial role to play in clinical and policy decision-making. The quality of much prognosis research is poor, evidenced by incomplete reporting, poor data sharing, incomplete registrations, and absent study protocols. Initiatives to improve transparency in trials include reporting guidelines, data pooling, registers, and journal requirements for protocols. Prognosis research could be transformed by similar initiatives. Routine registration of all prognostic studies, linked to an accessible study protocol using agreed reporting guidelines, would improve transparency and promote data sharing. Concern about applying transparency methods to observational research could be resolved by flexibility to update date-stamped protocols during prognosis studies.

Item Type: Article
Additional Information: PROGRESS Group. This is the final published version of the article (version of record). It first appeared online via Public Library of Science at http://dx.doi.org/10.1371/journal.pmed.1001671 please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: biomedical research, clinical protocols, humans, information dissemination, prognosis, vital statistics
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine and Health Sciences > Primary Care Health Sciences
Related URLs:
Depositing User: Symplectic
Date Deposited: 24 Mar 2017 15:24
Last Modified: 01 Apr 2019 08:48
URI: http://eprints.keele.ac.uk/id/eprint/3073

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