Cooper, DA and Robbins, E and Tizzard, GJ and Coles, SJ and O'Brien, M (2017) Furanyl Cyclic Ethers: Single and Double Diastereoselectivity in the Synthesis of 2,4-Di and 2,4,5-Trisubstituted Tetrahydropyrans. Journal Of Organic Chemistry, 82 (7). pp. 3441-3455. ISSN 0022-3263

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Abstract

Combining the desymmetrization of a prochiral bis-hydroxymethyl group with the epimerization of a chiral furanyl ether in a single transformation, high levels of double diastereoselectivity have been achieved in a synthesis of 2,4,5-trisubstituted tetrahydropyrans, which proceeds under thermodynamic control.

Item Type: Article
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Natural Sciences > School of Chemical and Physical Sciences
Related URLs:
Depositing User: Symplectic
Date Deposited: 11 Apr 2017 15:19
Last Modified: 26 Apr 2017 10:25
URI: http://eprints.keele.ac.uk/id/eprint/3210

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