Lee, H, Mansell, G, McAuley, JH, Kamper, SJ, Hubscher, M, Moseley, GL, Wolfenden, L, Hodder, RK and Williams, CM (2017) Casual mechanisms in the clinical course and treatment of back pain. Best Practice and Research: Clinical Rheumatology, 30 (6). pp. 1074-1083. ISSN 1532-1770

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Abstract

In recent years, there has been increasing interest in studying causal mechanisms in the development and treatment of back pain. The aim of this article is to provide an overview of our current understanding of causal mechanisms in the field. In the first section, we introduce key concepts and terminology. In the second section, we provide a brief synopsis of systematic reviews of mechanism studies relevant to the clinical course and treatment of back pain. In the third section, we reflect on the findings of our review to explain how understanding causal mechanisms can inform clinical practice and the implementation of best practice. In the final sections, we introduce contemporary methodological advances, highlight the key assumptions of these methods, and discuss future directions to advance the quality of mechanism-related studies in the back pain field.

Item Type: Article
Additional Information: This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Elsevier at https://doi.org/10.1016/j.berh.2017.04.001 Please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: Back pain; Mediation analysis; Mechanism; Casual inference
Subjects: ?? Back pain ??
?? Casual inference ??
?? Mechanism ??
?? Mediation analysis ??
R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
Divisions: Faculty of Medicine and Health Sciences > Primary Care Health Sciences
Depositing User: Symplectic
Date Deposited: 08 Jun 2017 13:19
Last Modified: 07 Jun 2018 12:30
URI: http://eprints.keele.ac.uk/id/eprint/3574

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