Judd, Amy Maryanne (2013) An investigation into the role of dendrimers as potential enhancers of the dermal delivery of topically applied chlorhexidine. Doctoral thesis, Keele University.

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Abstract

The reduction of bacteria on the skin results in prophylactic and therapeutic benefits by reducing the occurrence of skin infections. Currently, chlorhexidine digluconate, a conventional topical antiseptic, permeates the skin poorly leaving viable opportunistic pathogens below the superficial layers of the stratum corneum. The aim of this study was to use polyamidoamine (PAMAM) dendrimers to enhance the topical delivery of chlorhexidine digluconate to improve its antimicrobial efficacy.

Item Type: Thesis (Doctoral)
Uncontrolled Keywords: bacteria skin infections polyamidoamine dendrimers PAMAM chlorhexidine digluconate
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Medicine and Health Sciences > Institute for Science and Technology in Medicine
Depositing User: Michael Debenham
Date Deposited: 31 Mar 2015 12:45
Last Modified: 31 Mar 2015 12:45
URI: http://eprints.keele.ac.uk/id/eprint/381

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