Matthew O'Brien m.obrien@keele.ac.uk
An open-source approach to automation in organic synthesis: The flow chemical formation of benzamides using an inline liquid-liquid extraction system and a homemade 3-axis autosampling/product-collection device
O'Brien, M; Hall, A; Schrauwen, J; van der Made, J
Authors
A Hall
J Schrauwen
J van der Made
Abstract
Several open-source hardware and software technologies (RAMPS, Python, PySerial, OpenCV) were used to control an automated flow chemical synthesis system. The system was used to effect the synthesis of a series of benzamides. An inexpensive Raspberry Pi single board computer provided an electronic interface between the control computer and the RAMPS motor driver boards.
Acceptance Date | Feb 19, 2018 |
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Publication Date | Feb 21, 2018 |
Publicly Available Date | Mar 29, 2024 |
Journal | Tetrahedron |
Print ISSN | 0040-4020 |
Publisher | Elsevier |
Pages | 3152-3157 |
DOI | https://doi.org/10.1016/j.tet.2018.02.043 |
Keywords | Low-cost-automation; Open-source; Python; OpenCV; Raspberry-Pi; Flow-chemistry; Amide-formation; Liquid-liquid extraction |
Publisher URL | https://doi.org/10.1016/j.tet.2018.02.043 |
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https://creativecommons.org/licenses/by-nc-nd/4.0/
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