Ahmadipour, S, Beswick, L and Miller, GJ ORCID: 0000-0001-6533-3306 (2018) Recent advances in the enzymatic synthesis of sugar-nucleotides using nucleotidylyltransferases and glycosyltransferases. Carbohydrate Research, 469. 38 - 47. ISSN 0008-6215

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Abstract

Sugar-nucleotides are imperative to carbohydrate metabolism and glycoconjugate biosynthesis. Enzymatic methods to access these key materials offer a powerful alternative to traditional chemical synthesis routes. Herein we review recent advances in the enzymatic pyrophosphorylation of glycosyl 1-phosphates for the provision of both native and modified sugar-nucleotides.

Item Type: Article
Additional Information: This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Elsevier at https://doi.org/10.1016/j.carres.2018.09.002 - please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: Sugar-nucleotide, Glycosyl-1-phosphate, Pyrophosphorylase, Enzymatic synthesis, Nucleotidylyltransferase
Subjects: Q Science > QD Chemistry > QD415 Biochemistry
Divisions: Faculty of Natural Sciences > School of Chemical and Physical Sciences
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Depositing User: Symplectic
Date Deposited: 06 Nov 2018 14:00
Last Modified: 06 Nov 2018 14:02
URI: http://eprints.keele.ac.uk/id/eprint/5483

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