Foulkes, R, Ali Asgari, M, Curtis, A and Hoskins, C ORCID: https://orcid.org/0000-0002-7200-0566 (2019) Silver Nanoparticle-Mediated Therapies in the Treatment of Pancreatic Cancer. ACS Applied Nano Materials.

[img] Text
Manuscript REVISED .docx - Accepted Version
Restricted to Repository staff only until 12 March 2020.
Available under License Creative Commons Attribution Non-commercial.

Download (521kB)

Abstract

Pancreatic cancer is an extremely aggressive disease for which patient prognosis is poor and survival is extremely unlikely. It is an extremely under-represented cancer in the research field, due to the dense tumors formed and complexities surrounding treatment requirements. The use of nanomedicines in cancer therapy has been explored over the past few decades. Such nanomedicines are slowly coming to fruition in the clinical setting. One such platform which may possess promise in the fight against pancreatic cancer is the use of colloidal silver. Silver nanoparticles have shown potential in other cancer types over a host of treatment strategies and these are likely to be translatable into pancreatic cancer. This review will focus on the potential use of silver nanoparticles in pancreatic cancer therapy, reporting on a range of different strategies being employed which may be directly applicable in improving the clinical outcomes for pancreatic cancer patients.

Item Type: Article
Additional Information: The final published version of this article is available online at https://pubs.acs.org/doi/10.1021/acsanm.9b00439#
Uncontrolled Keywords: Pancreatic cancer, silver nanoparticles, cancer therapy, thermal therapy, antimicrobial, drug delivery
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Medicine and Health Sciences > School of Pharmacy
Depositing User: Symplectic
Date Deposited: 15 Mar 2019 08:59
Last Modified: 20 Mar 2019 08:50
URI: http://eprints.keele.ac.uk/id/eprint/6054

Actions (login required)

View Item View Item