Garriga, C, Murphy, J, Leal, J, Price, A, Prieto-Alhambra, D, Carr, A, Arden, N, Rangan, A, Cooper, C, Peat, G ORCID: https://orcid.org/0000-0002-9008-0184, Fitzpatrick, R, Barker, K and Judge, A (2019) Impact of a National Enhanced Recovery After Surgery Programme on Patient Outcomes of Primary total Knee Replacement: an Interrupted Time Series Analysis from “The National Joint Registry of England, Wales, Northern Ireland and the Isle of Man”. Osteoarthritis and Cartilage.

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Abstract

Objective
We aimed to test whether a national Enhanced Recovery After Surgery (ERAS) Programme in total knee replacement (TKR) had an impact on patient outcomes. Design Natural-experiment (April 2008-December 2016). Interrupted time-series regression assessed impact on trends before-during-after ERAS implementation.

Setting
Primary operations from the UK National Joint Registry were linked with Hospital Episode Statistics data which contains inpatient episodes undertaken in NHS trusts in England, and PROMs. Participants Patients undergoing primary planned TKR aged ≥18 years. Intervention ERAS implementation (April 2009-March 2011).

Outcomes
Regression coefficients of monthly means of LOS, bed day costs, change in Oxford knee scores (OKS) 6-months after surgery, complications (at 6 months), and rates of revision surgeries (at 5 years). Results 486,579 primary TKRs were identified. Overall LOS and bed-day costs decreased from 5.8 days to 3.7 and from £7607 to £5276, from April 2008 to December 2016. OKS change improved from 15.1 points in April 2008 to 17.1 points in December 2016. Complications decreased from 4.1 % in April 2008 to 1.7 % March 2016. 5-year revision rates remained stable at 4.8 per 1000 implants years in April 2008 and December 2011. After ERAS, declining trends in LOS and bed costs slowed down; OKS improved, complications remained stable, and revisions slightly increased.

Conclusions
Different secular trends in outcomes for patients having TKR have been observed over the last decade. Although patient outcomes are better than a decade ago ERAS did not improve them at national level.

Item Type: Article
Additional Information: This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Elsevier at https://doi.org/10.1016/j.joca.2019.05.001 - please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: Knee Replacement, Osteoarthritis, Enhanced Recovery, Epidemiology, Patient Outcomes, Time series, Bed Day Cost
Divisions: Faculty of Medicine and Health Sciences > Primary Care Health Sciences
Depositing User: Symplectic
Date Deposited: 10 May 2019 11:45
Last Modified: 10 May 2019 11:45
URI: http://eprints.keele.ac.uk/id/eprint/6315

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