Mohamed, M, Kinnaird, T, Anderson, R, Rashid, M, Martin, GP, Freeman, P, Kwok, CS ORCID: https://orcid.org/0000-0001-7047-1586, Myint, P, Zaman, AG and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2019) Combinations of bleeding and ischemic risk and their association with clinical outcomes in acute coronary syndrome. International Journal of Cardiology. (In Press)

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Abstract

Acute coronary syndromes (ACS) are an important cause of morbidity and mortality worldwide. Current guidelines recommend early management with potent antiplatelet agents and an early invasive coronary intervention strategy for both non-ST elevation myocardial infarction (NSTEMI) and ST-elevation myocardial infarction (STEMI). The mainstay of pharmacologic treatment for ACS is the use of potent antithrombotic therapy to minimize the risk for further ischemic events, which comes at an expense of an increased risk of bleeding complications that are associated with high rates of morbidity and mortality.

Item Type: Article
Additional Information: This is the accepted author manuscript (AAM). The final published version (version of record) will be available online via Elsevier at http://www.journals.elsevier.com/international-journal-of-cardiology/ - please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: GRACE, CRUSADE, risk scores, outcomes, treatment
Subjects: R Medicine > RC Internal medicine > RC666 Diseases of the circulatory (Cardiovascular) system
Divisions: Faculty of Medicine and Health Sciences > Institute for Science and Technology in Medicine
Depositing User: Symplectic
Date Deposited: 16 May 2019 08:40
Last Modified: 17 May 2019 13:43
URI: http://eprints.keele.ac.uk/id/eprint/6339

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