Rafferty, Paul (1978) Rearrangement and cycloaddition routes to novel heterocyclic systems. Doctoral thesis, Keele University.

[img]
Preview
Text
RaffertyPhD1978.pdf

Download (7MB) | Preview

Abstract

Part I of this thesis describes the treatment of tetrahydro-4-oxoisoxazolo[2,3-alpyridinium, phenyl hydrazone (70) with boiling acetic anhydride to give pyrazolo [4,3-b]pyridine (75) and the pyrrolo[3,2-b] pyridone (74)» or on longer heating, further acetylation to give compounds (78) and (79) plus tri-N-
(acetyl)phenylhydrazine (75)» The Introduction to Part I contains a brief review of the reaction of nucleophiles with differing substituted isoxazolium salts. Part II contains the synthesis of pyrido[3,2-c]pyridazine (87) from 2-vinyl pyridine (90) and diesters of azodicarboxylic acid. The synthesis is then extended to include other vinyl heterocyclic systems. The Introduction gives a review of addition of dienophiles to vinyl heterocyclic compounds with a brief summary of cycloaddition and ene reactions of diesters of azodicarboxylic acid.

Item Type: Thesis (Doctoral)
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Natural Sciences > School of Chemical and Physical Sciences
Contributors: Jones, G (Thesis advisor)
Depositing User: Lisa Bailey
Date Deposited: 24 Sep 2019 14:11
Last Modified: 24 Sep 2019 14:11
URI: http://eprints.keele.ac.uk/id/eprint/6879

Actions (login required)

View Item View Item