Venables, RH (2015) The application of tribology in assessing texture perception of oral liquid medicine. International Journal of Pharmaceutics, 479 (2). 277 - 281.

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Abstract

The palatability of medicines is likely to have a significant impact on patient adherence and consequently, on the safety and efficacy of a medicinal product. Palatability encompasses properties of medicines not limited to taste including swallowability (e.g. size, shape, texture). However, there has been limited work undertaken to measure the texture of medicines and how this may affect palatability and subsequent adherence.

Tribology offers an understanding of oral processes and can allow physical properties of materials to be linked to “mouthfeel”. This paper describes a preliminary application of tribology to oral liquid medicines and demonstrates that this technique is useful in the development of future oral liquid medicines.

Item Type: Article
Uncontrolled Keywords: tribology; texture; mouthfeel; medicine
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine and Health Sciences > Institute for Science and Technology in Medicine
Depositing User: Symplectic
Date Deposited: 13 Aug 2015 10:04
Last Modified: 09 May 2019 14:42
URI: http://eprints.keele.ac.uk/id/eprint/795

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