Garwood, K and McLaughlin, T and Garwood, C and Joens, S and Morrison, N and Taylor, CF and Carroll, K and Evans, C and Whetton, AD and Hart, S and Stead, D and Yin, Z and Brown, AJ and Hesketh, A and Chater, K and Hansson, L and Mewissen, M and Ghazal, P and Howard, J and Lilley, KS and Gaskell, SJ and Brass, A and Hubbard, SJ and Oliver, SG and Paton, NW (2004) PEDRo: a database for storing, searching and disseminating experimental proteomics data. BMC Genomics, 5. 68 - ?. ISSN 1471-2164

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Abstract

BACKGROUND: Proteomics is rapidly evolving into a high-throughput technology, in which substantial and systematic studies are conducted on samples from a wide range of physiological, developmental, or pathological conditions. Reference maps from 2D gels are widely circulated. However, there is, as yet, no formally accepted standard representation to support the sharing of proteomics data, and little systematic dissemination of comprehensive proteomic data sets. RESULTS: This paper describes the design, implementation and use of a Proteome Experimental Data Repository (PEDRo), which makes comprehensive proteomics data sets available for browsing, searching and downloading. It is also serves to extend the debate on the level of detail at which proteomics data should be captured, the sorts of facilities that should be provided by proteome data management systems, and the techniques by which such facilities can be made available. CONCLUSIONS: The PEDRo database provides access to a collection of comprehensive descriptions of experimental data sets in proteomics. Not only are these data sets interesting in and of themselves, they also provide a useful early validation of the PEDRo data model, which has served as a starting point for the ongoing standardisation activity through the Proteome Standards Initiative of the Human Proteome Organisation.

Item Type: Article
Subjects: Q Science > QH Natural history
Divisions: Faculty of Medicine and Health Sciences > Institute for Science and Technology in Medicine
Related URLs:
Depositing User: Symplectic
Date Deposited: 10 Sep 2015 08:01
Last Modified: 10 Sep 2015 08:01
URI: http://eprints.keele.ac.uk/id/eprint/856

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