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Welcome to Keele Repository

The Keele Repository is intended to be an Open Access showcase for the published research output of the university. Whenever possible, refereed documents accepted for publication, or finished artistic compositions presented in public, will be made available here in full digital format, and hyperlinks to standard published versions will be provided.



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Provision of positive and negative selections in retroviral vectors containing the cytosine deaminase gene (1998)
Journal Article

The E. coli cytosine deaminase (CD) provides a negative selection system for suicide gene therapy as CD transfectants are eliminated following 5-fluorocytosine (5FC) treatment. Here we report a positive selection system for the CD gene using 5-fluoro... Read More about Provision of positive and negative selections in retroviral vectors containing the cytosine deaminase gene.