Hasenkamp, S and Sidaway, A and Devine, O and Roye, R and Horrocks, P (2013) Evaluation of bioluminescence-based assays of anti-malarial drug activity. Malaria Journal, 12. 58 - ?. ISSN 1475-2875

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Abstract

Transgenic Plasmodium falciparum expressing luciferase offers an attractive bioluminescence-based assay platform for the investigation of the pharmacological properties of anti-malarial drugs. Here a side-by-side comparison of bioluminescence and fluorescence-based assays, utilizing a luciferase reporter cassette that confers a strong temporal pattern of luciferase expression during the S-phase of intraerythrocytic development, is reported.

Item Type: Article
Uncontrolled Keywords: luciferase, sybr green I, antimalarial drug, relative rate of kill, malaria
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Natural Sciences > School of Life Sciences
Related URLs:
Depositing User: Symplectic
Date Deposited: 26 Nov 2014 13:14
Last Modified: 28 Jul 2017 15:34
URI: http://eprints.keele.ac.uk/id/eprint/98

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