Hasenkamp, S and Sidaway, A and Devine, O and Roye, R and Horrocks, P (2013) Evaluation of bioluminescence-based assays of anti-malarial drug activity. Malaria Journal, 12. 58 - ?. ISSN 1475-2875
Evaluation of bioluminescence-based assays of anti-malarial drug activity..pdf - Published Version
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Transgenic Plasmodium falciparum expressing luciferase offers an attractive bioluminescence-based assay platform for the investigation of the pharmacological properties of anti-malarial drugs. Here a side-by-side comparison of bioluminescence and fluorescence-based assays, utilizing a luciferase reporter cassette that confers a strong temporal pattern of luciferase expression during the S-phase of intraerythrocytic development, is reported.
|Uncontrolled Keywords:||luciferase, sybr green I, antimalarial drug, relative rate of kill, malaria|
|Subjects:||Q Science > QH Natural history > QH301 Biology|
|Divisions:||Faculty of Natural Sciences > School of Life Sciences|
|Date Deposited:||26 Nov 2014 13:14|
|Last Modified:||18 Sep 2015 12:53|
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