Goksel Misirli g.misirli@keele.ac.uk
Receiver Design Using Genetic Circuits in Molecular Communication
Misirli
Authors
Abstract
Understanding the dynamics of molecular communications between cells and intracellular response is crucial to create predictable cellular applications. When the propagation mechanism is diffusion based, the arrival histogram of molecules becomes heavy tailed and the stray molecules create interference for the following symbol slots. Here, we present a model-based framework to design diffusion-based systems using computer simulations. To overcome interference problems, we utilize two different signals with two different molecule types to carry a single bit of data. While the first signal is the actual data carrier, the latter acts as an antagonist to cancel out the heavy tail of the former signal. At the receiver side, these signals are used to control cellular behaviour via a synthetic genetic circuit, which eliminates the effect of stray molecules. This holistic and model-driven design approach combines both intracellular and intercellular dynamics to create novel applications.
Conference Name | 4th workshop on Molecular Communications |
---|---|
Conference Location | Linz, Austria |
Start Date | Apr 16, 2019 |
End Date | Apr 18, 2019 |
Acceptance Date | Mar 18, 2019 |
Publication Date | Apr 18, 2019 |
Series Title | 4th workshop on Molecular Communications |
Keywords | Synthetic biology, molecular communications, diffusion, genetic circuits, model-driven design, automation |
Publisher URL | https://molecularcommunications.eu/ |
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