Keele Research Repository

A

Abdullah, MI, Abed, MN and Richardson, A ORCID: https://orcid.org/0000-0003-1825-3375 (2017) Inhibition of the mevalonate pathway augments the activity of pitavastatin against ovarian cancer cells. Scientific Reports, 7 (1). 8090 -?.

Adams, C.F., Sen, J, Tickle, JA, Tzerakis, N and Chari, DM (2017) Developing human dish models of neurological pathology. Midlands Medicine, 27 (4).

Al Shakarchi, W, Varbiro, G, Curtis, A and Hoskins, C ORCID: https://orcid.org/0000-0002-7200-0566 (2017) The co-administration of anticancer and pro-apoptotic agents as novel approach in liver cancer therapy. In: European Nanomedicine Meeting, 03/04/2017 - 04/04/2017, London. (Unpublished)

Al-Azzawi, Buthainah (2017) A role for the human mesenchymal stem cell secretome in attenuation of cytokine-induced apoptosis in pancreatic beta cells. Doctoral thesis, Keele University.

Al-Dulaimi, Omar Ahmed Abass (2017) Phytochemical Composition and Antimicrobial Properties of Four Plants Indicated for Traditional Medicine Use. Doctoral thesis, Keele University.

Al-Mayyahi, Rawaa Salim (2017) An investigation of the mechanisms underpinning the effect of anti-inflammatory drugs on neural stem cells. Doctoral thesis, Keele University.

Aldulami, O, Uche, F, Hameed, H, Mbye, H, Ullah, I, Drijfhout, F, Claridge, T, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Li, W (2017) A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms. Journal of Ethnopharmacology, 198. pp. 221-225.

Alghannam, Abdullah Mohammed (2017) Investigating the effects of nicergoline on calcium signalling in human platelets and megakaryocytes. Masters thesis, Keele University.

Allan, R, Sharples, AP, Close, GL, Drust, B, Shepherd, SO, Dutton, J, Morton, JP and Gregson, W (2017) Post-exercise cold-water immersion modulates skeletal muscle PGC-1α mRNA expression in immersed and non-immersed limbs: evidence of systemic regulation. Journal of Applied Physiology. -.

Anand, Peterson (2017) The function of sodium/calcium ion exchanger in human platelets and megakaryocytes. Masters thesis, Keele University.

B

Bagur, R, Chamula, M, Brouillard, E, Lavi, S, Nombela-Franco, L, Julien, AS, Archambault, L, Varfalvy, N, Turcotte-Gosselin, F, Beaupré, F, Joncas, SX, Gaudreault, V, Parviz, Y, Teefy, PJ, Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890 and Lavoie, C (2017) Radiotherapy-induced cardiac implantable electronic device disorders in cancer patients. American Journal of Cardiology, 119 (2). pp. 284-289.

Bagur, R, Solo, K, Alghofaili, S, Nombela-Franco, L, Kwok, CS, Hayman, S, Siemieniuk, RA, Foroutan, F, Spencer, FA, Vandvik, PO, Schäufele, TG and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Cerebral Embolic Protection Devices During Transcatheter Aortic Valve Implantation: Systematic Review and Meta-analysis. Stroke, 48 (5). pp. 1306-1315.

Bake, T, Baron, J, Duncan, JS, Morgan, DGA and Mercer, JG (2017) Arcuate Nucleus Homeostatic Systems Reflect Blood Leptin Concentration but not Feeding Behaviour during Scheduled Feeding on a High Fat Diet in Mice. Journal of Neuroendocrinology, 29 (8). e12498.

Bardsley, K, Yang, Y and El Haj, AJ (2017) Fluorescent Labeling of Collagen Production by Cells for Noninvasive Imaging of Extracellular Matrix Deposition. Tissue Eng Part C Methods, 23 (4). 228 - 236.

Barlas, RS, McCall, SJ, Bettencourt-Silva, JH, Clark, AB, Bowles, KM, Metcalf, AK, Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890, Potter, JF and Myint, PK (2017) Impact of anaemia on acute stroke outcomes depends on the type of anaemia: Evidence from a UK stroke register. Journal of the Neurological Sciences, 383. pp. 26-30.

Beesoo, R, Bhagooli, R, Neergheen-Bhujun, V, Li, W, Kagansky, A and Bahorun, T (2017) Antibacterial and antibiotic potentiating activities of tropical marine sponge extracts. Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 196. pp. 81-90.

Bowerman, M, Becker, CG, Yáñez-Muñoz, RJ, Ning, K, Wood, MJA, Gillingwater, TH, Talbot, K and UK SMA Research Consortium, . (2017) Therapeutic strategies for spinal muscular atrophy: SMN and beyond. Disease Models and Mechanisms, 10 (8). 943 - 954.

Bowerman, M, Salsac, C, Bernard, V, Soulard, C, Dionne, A, Coque, E, Benlefki, S, Hince, P, Dion, PA, Butler-Browne, G, Camu, W, Bouchard, J-P, Delpire, E, Rouleau, GA, Raoul, C and Scamps, F (2017) KCC3 loss-of-function contributes to Andermann syndrome by inducing activity-dependent neuromuscular junction defects. Neurobiology of Disease, 106. 35 - 48.

Brown, AD, Close, GL, Sharples, AP and Stewart, CE (2017) Murine myoblast migration: influence of replicative ageing and nutrition. Biogerontology (10.100).

Brown, S ORCID: https://orcid.org/0000-0001-9671-7054, Rodrigues, S, Sharp, C, Wade, K, Broom, N, McCall, IW and Roberts, S (2017) Staying connected: structural integration at the intervertebral disc-vertebra interface of human lumbar spines. European Spine Journal, 26 (1). 248 -258.

Butler, R, Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 and Sandhu, K (2017) Endothelial progenitor cells: exploring the pleiotropic effects of statins. World Journal of Cardiology, 9 (1). pp. 1-13.

C

Cabrera, D, Lak, A, Yoshida, T, Materia, ME, Ortega, D, Ludwig, F, Guardia, P, Sathya, A, Pellegrino, T and Teran, FJ (2017) Unraveling viscosity effects on the hysteresis losses of magnetic nanocubes. Nanoscale, 9 (16). 5094 - 5101.

Cameron, D, Morden, JP, Canney, P, Velikova, G, Coleman, R, Bartlett, J, Agrawal, R, Banerji, J, Bertelli, G, Bloomfield, D, Brunt, AM, Earl, H, Ellis, P, Gaunt, C, Gillman, A, Hearfield, N, Laing, R, Murray, N, Couper, N, Stein, RC, Verrill, M, Wardley, A, Barrett-Lee, P and Bliss, JM (2017) Accelerated versus standard epirubicin followed by cyclophosphamide, methotrexate, and fluorouracil or capecitabine as adjuvant therapy for breast cancer in the randomised UK TACT2 trial (CRUK/05/19): a multicentre, phase 3, open-label, randomised, controlled trial. The Lancet Oncology, 18 (7). 929 - 945.

Carmont, MR, Kuiper, JH, Grävare Silbernagel, K, Karlsson, J and Nilsson-Helander, K (2017) Tendon end separation with loading in an Achilles tendon repair model: comparison of non-absorbable vs. absorbable sutures. Journal of Experimental Orthopaedics.

Chapman, SR ORCID: https://orcid.org/0000-0002-0326-7742, Fitzpatrick, R and Aladul, M (2017) Has cost inhibited the uptake of more potent statins in England? Pharmacoepidemiology and Drug Safety, 26 (8). pp. 984-991.

Chapman, SR ORCID: https://orcid.org/0000-0002-0326-7742, Fitzpatrick, RW and Aladul, MI ORCID: https://orcid.org/0000-0002-7368-3469 (2017) Knowledge, attitude and practice of healthcare professionals towards infliximab and insulin glargine biosimilars: result of a UK web-based survey. BMJ Open, 7 (6). e016730 - ?.

Chapman, SR ORCID: https://orcid.org/0000-0002-0326-7742, Naughton, B, Brindley, D, Roberts, L and Dopson, S (2017) Medicine authentication technology as a counterfeit medicine-detection tool: a Delphi method study to establish expert opinion on manual medicine authentication technology in secondary care. BMJ Open, 7 (5).

Chapman, V, Markides, H, Sagar, DR, Xu, L, Burston, JJ, Mapp, P, Kay, A, Morris, RH, Kehoe, O and El Haj, AJ (2017) Therapeutic Benefit for Late, but Not Early, Passage Mesenchymal Stem Cells on Pain Behaviour in an Animal Model of Osteoarthritis. Stem Cells International, 2017. 2905104 - ?.

Cheung, DG, Buzzetti, M and Di Leva, G (2017) miRNAs in bone metastasis. Expert Review of Endocrinology and Metabolism, 12 (6). pp. 451-461.

Choudhury, TR, Al-Saigh, S, Burley, S, Li, L, Shakhshir, N, Mirhosseini, N, Wang, T, Arnous, S, Khan, MA, Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890 and Fraser, DGW (2017) Longitudinal deformation bench testing using a coronary artery model: a new standard? Open Heart, 4 (2).

Chue, CD, Kwok, CS, Wong, CW, Patwala, A, Barker, D, Zaidi, A, Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890, Cunnington, C and Ahmed, FZ (2017) Efficacy And Safety Of The Subcutaneous Implantable Cardioverter Defibrillator: A Systematic Review. Heart, 103 (17). pp. 1315-1322.

Coles, C, Griffin, C, Kirby, A, Agrawal, R, Alhasso, A, Bhattacharya, I, Brunt, AM ORCID: https://orcid.org/0000-0002-4797-5097, Ciurlionis, L, Chan, H, Donovan, E, Emson, M, Harnett, A, Haviland, J, Hopwood, P, Jefford, M, Kaggwa, R, Sawyer, E, Sybdikus, I, Tsang, Y, Wheatley, D, Wilcox, M, Yarnold, J and Bliss, J (2017) Partial breast radiotherapy after breast conservation: 5 year outcomes from the IMPORT LOW (CRUK/06/003) phase III trial. Radiotherapy and Oncology, 123 (S1). S162 -S163.

D

Davies, B, Gilchrist, FJ, Saunders, A and Carroll, W (2017) Annual hospitalisation rates for children with asthma are inversely associated with total hours of sunshine in English regions. Clinical and Experimental Allergy, 47 (6). pp. 838-840.

De Santi, C, Melaiu, O, Bonotti, A, Cascione, L, Di Leva, G, Foddis, R, Cristaudo, A, Lucchi, M, Mora, M, Truini, A, Tironi, A, Murer, B, Boldorini, R, Cipollini, M, Gemignani, F, Gasparini, P, Mutti, L and Landi, S (2017) Deregulation of miRNAs in malignant pleural mesothelioma is associated with prognosis and suggests an alteration of cell metabolism. Scientific Reports, 7 (1). 3140-?.

Dugdale, HF, Hughes, DC, Allan, R, Deane, CS, Coxon, CR, Morton, JP, Stewart, CE and Sharples, AP (2017) The role of resveratrol on skeletal muscle cell differentiation and myotube hypertrophy during glucose restriction. Molecular and Cellular Biochemistry.

Duncan, G, Firth, K, George, V ORCID: https://orcid.org/0000-0002-8498-9965, Hoang, MD, Staniforth, A, Smith, G and Denning, C (2017) Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Stem Cells and Development, 26 (23). 1695 -1705.

de Jong, AJ, Klein-Wieringa, IR, Andersen, SN, Kwekkeboom, JC, Herb-van Toorn, L, de Lange-Brokaar, BJE, van Delft, D, Garcia, J, Wei, W, van der Heide, HJL, Bastiaansen-Jenniskens, YM, van Osch, GJVM, Zuurmond, AM, Stojanovic-Susulic, V, Nelissen, RGHH, Toes, REM, Kloppenburg, M and Ioan-Facsinay, A (2017) Lack of high BMI-related features in adipocytes and inflammatory cells in the infrapatellar fat pad (IFP). Arthritis Research & Therapy, 19 (1). 186 - ?.

de Wolf, E, Abdullah, MI, Jones, SM, Menezes, K, Moss, DM, Drijfhout, FP ORCID: https://orcid.org/0000-0002-3210-8038, Hart, S, Hoskins, C ORCID: https://orcid.org/0000-0002-7200-0566, Stronach, EA and Richardson, A ORCID: https://orcid.org/0000-0003-1825-3375 (2017) Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer. Scientific Reports, 7 (1).

E

Evans, MG, Al-Shakli, A, Jenkins, SI and Chari, DM (2017) Electrophysiological Assessment of Primary Cortical Neurons Genetically Engineered using Iron Oxide Nanoparticles. Nano Research, 10 (8). pp. 2881-2890.

Evans, MG, Shakli, A, Jenkins, SI and Chari, DM (2017) Electrophysiological assessment of primary cortical neurons genetically engineered using iron oxide nanoparticles. Nano Research, 10 (8). pp. 2881-2890.

F

Ferro, CJ, Law, J, Doshi, S, DeBelder, M, Moat, N, Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890, Hildick-Smith, D, Townend, J and Ludman, P (2017) Dialysis following Transcatheter Aortic Valve Implantation: risk factors and outcomes: An analysis from the UK TAVI Registry. JACC: Cardiovascular Interventions, 10 (20). pp. 2040-2047.

Fisher, AG, Seaborne, RA, Hughes, TM, Gutteridge, A, Stewart, C, Coulson, JM, Sharples, AP and Jarvis, JC (2017) Transcriptomic and epigenetic regulation of disuse atrophy and the return to activity in skeletal muscle. FASEB J, 31 (12). 5268 - 5282.

Foldager, CB, Bendtsen, M, Berg, LC, Brinchmann, JE, Brittberg, M, Bunger, C, Canseco, J, Chen, L, Christensen, BB, Colombier, P, Deleuran, BW, Edwards, J, Elmengaard, B, Farr, J, Gatenholm, B, Gomoll, AH, Hui, JH, Jakobsen, RB, Joergensen, NL, Kassem, M, Koch, T, Kold, S, Krogsgaard, MR, Lauridsen, H, Le, D, Le Visage, C, Lind, M, Nygaard, JV, Olesen, ML, Pedersen, M, Rathcke, M, Richardson, JB, Roberts, S, Rölfing, JHD, Sakai, D, Toh, WS, Urban, J and Spector, M (2017) Aarhus Regenerative Orthopaedics Symposium (AROS). Acta Orthopaedica, 87 (sup363). 1 - 5.

Fouriki, Angeliki (2017) Oscillating magnet array-based nanomagnetic gene transfection of mammalian cells relevant to regenerative medicine. Doctoral thesis, Keele University.

Frisher, M (2017) Alcohol consumption, wealth and health. The Lancet Public Health, 2 (8). e353 - e353.

Fuller, HR ORCID: https://orcid.org/0000-0001-8868-896X (2017) Reflections on an issue of student diversity: unintentional plagiarism among international students. Journal of Academic Development and Education (8).

Fuller, HR ORCID: https://orcid.org/0000-0001-8868-896X, Shorrock, HK, Gillingwater, TH, Pigott, A, Smith, V, Kulshrestha, R, Sewry, CS and Willis, TA (2017) Two cases of spinal muscular atrophy type II with eosinophilic oesophagitis. Journal of Neuromuscular Diseases, 4 (4). pp. 357-362.

G

Garcia, John K (2017) An in vitro study of the chondrogenic and immunomodulatory properties of mesenchymal stem cells from the osteoarthritic joint. Doctoral thesis, Keele University.

Griffin, SM, Pickard, MR, Orme, RP, Hawkins, SP, Williams, AC and Fricker, RA (2017) Nicotinamide alone accelerates the conversion of mouse embryonic stem cells into mature neuronal populations. PLoS One, 12. 1 -17.

H

Hackett, G, Cole, N, Saghir, A, Jones, P, Strange, RC and Ramachandran, S (2017) Testosterone replacement therapy: improved sexual desire and erectile function in men with type 2 diabetes following a 30-week randomized placebo-controlled study. Andrology, 5 (5). 905 - 913.

Harrison, R, Markides, H, Morris, RH, Richards, P, El Haj, AJ and Sottile, V (2017) Autonomous magnetic labelling of functional mesenchymal stem cells for improved traceability and spacial control in cell therapy applications. Journal of Tissue Engineering and Regenerative Medicine, 11 (8). pp. 2333-2348.

Hasan, AM and Dent, G (2017) Involvement of the α/β Isoform of p38 MAP Kinase in Chemotactic Responses of Human Eosinophils to Eotaxin (CCL11) and RANTES (CCL5). American Journal of Immunology, 13 (4). pp. 209-215.

Hasan, AM and Dent, G (2017) Involvement of the α/β Isoform of p38 MAP Kinase in Chemotactic Responses of Human Eosinophils to Eotaxin (CCL11) and RANTES (CCL5). American Journal of Immunology, 13 (4). 209 -215.

Heald, A, Anderson, S, Scargill, J, Short, A, Holland, D, Khan, A, Fryer, A, Donn, R and Livingston, M (2017) Social Disadvantage Is Associated With Lower Vitamin D Levels in Older People and There Is No Surrogate for Its Measurement. Gerontology and Geriatric Medicine, 3.

Hegab, Z, Mohamed, TMA, Stafford, N, Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890, Cartwright, EJ and Oceandy, D (2017) Advanced glycation end products reduce the calcium transient in cardiomyocytes by increasing production of reactive oxygen species and nitric oxide. FEBS Open Bio, 7 (11). 1672 -1685.

Hendrikson, WJ, Deegan, AJ, Yang, Y, van Blitterswijk, CA, Verdonschot, N, Moroni, L and Rouwkema, J (2017) Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation. Frontiers in Bioengineering and Biotechnology, 5. pp. 1-11.

Hmeidi, H, Motamedi-Fakhr, S, Chadwick, EKJ, Gilchrist, FJ, Lenney, W, Iles, R, Wilson, RC and Alexander, J (2017) Tidal breathing parameters measured using structured light plethysmography in healthy children and those with asthma before and after bronchodilator. Physiological Reports, 5 (5).

Holmes, AM, Scurr, DJ, Heylings, JR, Wan, K-W and Moss, GP (2017) Dendrimer pre-treatment enhances the skin permeation of chlorhexidine digluconate: Characterisation by in vitro percutaneous absorption studies and Time-of-Flight Secondary Ion Mass Spectrometry. European Journal of Pharmaceutical Sciences, 104. pp. 90-101.

Hoskins, C ORCID: https://orcid.org/0000-0002-7200-0566 (2017) Heat triggered theranostics for pancreatic cancer therapy. In: Cancer Nanotechnology 2017, 19/06/2017 - 22/06/2017, Vermont. (Unpublished)

Hulme, C, Wilson, E, Peffers, M, Fuller, H ORCID: https://orcid.org/0000-0001-8868-896X, Roberts, S, Simpson, D, Richardson, J, Gallacher, P and Wright, K (2017) Poor clinical response to Autologous Chondrocyte Implantation is associated with a unique synovial fluid proteome profile. Osteoarthritis and Cartilage, 25 (1). S92.

Hulme, C, Wilson, E, Peffers, M, Roberts, S, Simpson, D, Richardson, J, Gallacher, P and Wright, K (2017) Autologous chondrocyte implantation- derived synovial fluids display distinct responder and non-responder proteomic profiles. Arthritis Research and Therapy, 19 (1).

Hulme, W, Sperrin, M, Kontopantelis, E, Ratib, K, Ludman, P, Sirker, A, Kinnaird, T, Curzen, N, Kwok, CS ORCID: https://orcid.org/0000-0001-7047-1586, Debelder, M, Nolan, J and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Increased radial access is not associated with worse femoral outcomes for PCI in the United Kingdom. Circulation: Cardiovascular Interventions, 10 (2). 004279.

I

Iqbal, J, Kwok, CS, Kontopantelis, E, de Belder, MA, Ludman, PF, Large, A, Butler, R, Gamal, A, Kinnaird, T, Zaman, A and Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Choice of Stent for Percutaneous Coronary Intervention of Saphenous Vein Grafts. Circulation: Cardiovascular Interventions, 10 (4).

Ismail, Y, Wimpenny, I, Bretcanu, O, Dalgarno, K and El Haj, AJ (2017) Development of multi-substituted hydroxyapatite nanopowders as biomedical materials for bone tissue engineering applications. Journal of Biomedical Materials Research Part A, 105 (6). pp. 1775-1785.

J

Johnson-Ajinwo, O, Richardson, A ORCID: https://orcid.org/0000-0003-1825-3375 and Li, W (2017) Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines. In: IUPHAR, 27-29 September 2017, Aberdeen.

Johnson-Ajinwo, Okiemute Rosa (2017) Identification, semi-synthesis and evaluation of anti-ovarian cancer compounds from plants used in traditional medicines. Doctoral thesis, Keele University.

K

Kalra, Seema (2017) Characterisation of pathogenic T helper and T regulatory cell subsets in relapse and progression in multiple sclerosis. Doctoral thesis, Keele University.

Kasper, AM, Turner, DC, Martin, NRW and Sharples, AP (2017) Mimicking exercise in three-dimensional bioengineered skeletal muscle to investigate cellular and molecular mechanisms of physiological adaptation. Journal of Cellular Physiology, 233 (3). pp. 1985-1998.

Kehoe, O, Kay, AG, Long, G, Tyler, G, Stefan, A, Broadfoot, SJ, Piccinini, AM and Middleton, J (2017) Mesenchymal Stem Cell- Conditioned Medium Reduces Disease Severity and Immune Responses in Inflammatory Arthritis. Scientific Reports, 7 (1).

Khare, V, Al Sakarchi, W, Gupta, PN, Curtis, ADM and Hoskins, C ORCID: https://orcid.org/0000-0002-7200-0566 (2017) Synthesis and characterization of TPGS-gemcitabine prodrug micelles for pancreatic cancer therapy. RSC ADVANCES, 7 (21). 12598 - 12598.

Khare, V, Sakarchi, WA, Gupta, PN, Curtis, ADM and Hoskins, C ORCID: https://orcid.org/0000-0002-7200-0566 (2017) Further correction: Synthesis and characterization of TPGS-gemcitabine prodrug micelles for pancreatic cancer therapy. RSC Advances, 7 (28). 17367 - 17367.

Kinnaird, T, Anderson, R, Ossei-Gerning, N, Gallagher, S, Large, A, Strange, J, Ludman, P, de Belder, M, Nolan, J, Hildick Smith, D and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Vascular access site and outcomes among 26,807 chronic total coronary occlusion angioplasty cases from the British Cardiovascular Interventions Society National database. JACC: Cardiovascular Interventions, 10 (7). pp. 635-644.

Kontopantelis, E, Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890, van Marwijk, H, Ryan, AM, Buchan, IE, Ashcroft, DM and Doran, T (2017) Geographical epidemiology of health and overall deprivation in England, its changes and persistence from 2004 to 2015: a longitudinal spatial population study. Journal of Epidemiology and Community Health, 72 (2). pp. 140-147.

Kotronias, R, Kwok, CS ORCID: https://orcid.org/0000-0001-7047-1586, George, S, Capodanno, D, Ludman, PF, Townend, JN, Doshi, SN, Khogali, S, Genereux, P, Herrmann, HC, Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 and Bagur, R (2017) Transcatheter Aortic Valve Implantation With or Without Percutaneous Coronary Artery Revascularization Strategy: A Systematic Review and Meta-analysis. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 6 (6).

Kwok, CS, Bagur, R, Rashid, M, Lavi, R, Cibelli, M, De Belder, M, Moat, N, Hildick-Smith, D, Ludman, P and Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Aortic Stenosis and Non-Cardiac Surgery: A Systematic Review and Meta-Analysis. International Journal of Cardiology, 240. pp. 145-153.

L

Lea, SC, Watts, KL, Davis, NA, Panayiotou, B, Bankart, MJ, Arora, A and Chambers, R (2017) The potential clinical benefits of medicines optimisation through comprehensive geriatric assessment, carried out by secondary care geriatricians, in a general practice care setting in North Staffordshire, UK: a feasibility study. BMJ Open, 7 (9). e015278 - ?.

Lefroy, J, Roberts, N, Molyneux, A, Bartlett, M, Gay, S and McKinley, RK ORCID: https://orcid.org/0000-0002-3684-3435 (2017) Utility of an app-based system to improve feedback following workplace-based assessment. International Journal of Medical Education, 8. pp. 207-216.

Liapi, L (2017) The Talke of the Towne: News, Crime and the Public Sphere in Seven. Cultural and Social History.

Liaskou, M, White, SJ, Moss, G, Ratcliffe, N and Cook, J (2017) Pharmacy staff perspectives on the role of community pharmacy in the provision of first aid and responding to emergencies: a qualitative study. International Journal of Pharmacy Practice, 25 (S1). 18 - 19.

Llavero Hurtado, M, Fuller, HR ORCID: https://orcid.org/0000-0001-8868-896X, Wong, AMS, Eaton, SL, Gillingwater, TH, Pennetta, G, Cooper, JD and Wishart, TM (2017) Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo. Scientific Reports (12412).

M

Malekigorji, M, Alfahad, M, Kong Thoo Lin, P, Jones, S, Curtis, ADM and Hoskins, C ORCID: https://orcid.org/0000-0002-7200-0566 (2017) Thermally Triggered Theranostics for Pancreatic Cancer Therapy. Nanoscale, 9 (34).

Mallows, A, Debenham, J, Walker, T and Littlewood, C (2017) Association of psychological variables and outcome in tendinopathy: a systematic review. British Journal of Sports Medicine, 51 (9). 743 - 748.

Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) One-month global longitudinal strain identifies patients who will develop pacing-induced left ventricular dysfunction over time: the pacing and ventricular dysfunction (PAVD) study. PLoS One, 12 (1).

Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890, Sperrin, M, Watson, MC, Coutts, A, Wilde, K, Burton, C, Kadam, UT, Kwok, CS, Clarke, AB, Murchie, P, Buchan, I, Hannaford, PC and Myint, PK (2017) Do patients have a worse outcome with heart failure than cancer? A primary care based cohort study with 10-year follow-up in Scotland. European Journal of Heart Failure, 19 (9). pp. 1095-1104.

Martin, G, Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890, Peek, N, Buchan, I and Sperrin, M (2017) Clinical Prediction in Defined Populations: a simulation study investigating when and how to aggregate existing models. BMC Medical Research Methodology, 17 (1). pp. 1-11.

Martin, G, Sperrin, M, Bagur, R, De Belder, MA, Buchan, I, Gunning, M, Ludman, P and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Pre-implantation Balloon Aortic Valvuloplasty and Clinical Outcomes Following Transcatheter Aortic Valve Implantation: A Propensity Score Analysis of the UK Registry. Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 6 (2).

Martin, G, Sperrin, M, Hulme, W, Ludman, PF, De Belder, MA, Toff, WD, Alabas, O, Moat, N, Doshi, S, Buchan, I, Deanfield, J, Gale, CP and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Relative survival following transcatheter aortic valve implantation: how do TAVI patients fare relative to the general population? Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 6 (10).

Martin, G, Sperrin, M, Ludman, P, Debelder, M, Redwood, S, Townend, J, Gunning, M, Moat, N, Banning, A, Buchan, I and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) A Novel UK Prognostic Model for 30-day Mortality following Transcatheter Aortic Valve Implantation. Heart, 104 (13). pp. 1109-1116.

Martin, GP, Kinnaird, T, Sperrin, M, Anderson, R, Gamal, A, Jabbar, A, Kwok, CS, Barker, D, Heatlie, G, Zaman, AG and Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Effect of weekend admission on process of care and clinical outcomes for the management of acute coronary syndromes: a retrospective analysis of three UK centres. BMJ Open, 7 (9). e016866 - ?.

Mathur, S and Hoskins, C ORCID: https://orcid.org/0000-0002-7200-0566 (2017) Drug development: Lessons from nature. Spandidos Publications.

Metcalfe, AJ, Stewart, CJ, Postans, NJ, Biggs, PR, Whatling, GM, Holt, CA and Roberts, AP (2017) Abnormal loading and functional deficits are present in both limbs before and after unilateral knee arthroplasty. Gait & Posture, 55. pp. 109-115.

Moise, S, Céspedes, E, Soukup, D, Byrne, JM, El Haj, AJ and Telling, ND (2017) The cellular magnetic response and biocompatibility of biogenic zinc- and cobalt-doped magnetite nanoparticles. Scientific Reports, 7. 39922 - ?.

Morris, AM, Clipstone, S, Stockton, W and Crawford, RM (2017) Longitudinal Investigation of Medical Student Perceptions of a Video-based Guided Study Resource used to Facilitate an Eight Week Module in Medicine. Journal of Pedagogic Development, 7 (1).

Moss, DM, Domanico, P, Watkinson, M ORCID: https://orcid.org/0000-0003-1877-5667, Seonghee, P, Randolph, R, Wring, S, Rajoli, RKR, Hobson, J, Rannard, S, Siccardi, M and Owen, A (2017) Simulating Intestinal Transporter and Enzyme Activity in a Physiologically Based Pharmacokinetic Model for Tenofovir Disoproxil Fumarate. Antimicrobial Agents and Chemotherapy, 61 (7).

Murphy, D, Mattey, D and Hutchinson, D (2017) Anti-citrullinated protein antibody positive rheumatoid arthritis is primarily determined by rheumatoid factor titre and the shared epitope rather than smoking per se. PLoS One, 12 (7). e0180655 - ?.

N

Nagaraja, V, Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890, Mahmoudi, M, Rogers, C and Curzen, N (2017) Change in angiogram-derived management strategy of patients with chest pain when some FFR data are available: How consistent is the effect? Cardiovascular Revascularization Medicine, 18 (5). pp. 320-327.

Naheed, B, Kuiper, JH, Uthman, OA, O'Mahony, F and O'Brien, PMS (2017) Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome. Cochrane Database of Systematic Reviews, 3. CD010503 - ?.

Nevatte, TM, Ward, RD, Sedda, L and Hamilton, JGC (2017) After infection with Leishmania infantum, Golden Hamsters (Mesocricetus auratus) become more attractive to female sand flies (Lutzomyia longipalpis). Scientific Reports, 7 (1).

Noman, A, Balasubramaniam, K, Alhous, MHA, Lee, K, Jesudason, P, Rashid, M, Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890 and Zaman, AG (2017) Mortality after percutaneous coronary revascularization: Prior cardiovascular risk factor control and improved outcomes in patients with diabetes mellitus. Catheterization and Cardiovascular Interventions, 89 (7). pp. 1195-1204.

O

Ogrodnik, P (2017) Metaphysis. The Parlimentary Review.

Ogrodnik, P and Thomas, PBM (2017) A Practical Fracture Healing Endpoint Assessment Criterion For Tibial Fractures Treated With External Fixation. In: European Federation of National Associations Of Orthopaedics and Traumatology, 31 May - 2 Jun 2017, Vienna. (In Press)

Oluwasanmi, A, Al Shakarchi, W, Manzur, A, Aldebasi, M, Elsini, R, Albusair, M, Haxton, K, Curtis, ADM and Hoskins, C ORCID: https://orcid.org/0000-0002-7200-0566 (2017) Diels Alder-mediated release of gemcitabine from hybrid nanoparticles for enhanced pancreatic cancer therapy. Journal of Controlled Release, 266. pp. 355-364.

Oluwasanmi, Adeolu (2017) Diels Alder-mediated release of gemcitabine from nanoparticles: developing improved methods for pancreatic cancer drug delivery. Doctoral thesis, Keele University.

Owida, HA, De Las Heras Ruiz, T, Dhillon, A, Yang, Y ORCID: https://orcid.org/0000-0002-1362-6040 and Kuiper, NJ (2017) Co-culture of chondrons and mesenchymal stromal cells reduces the loss of collagen VI and improves extracellular matrix production. Histochemistry and Cell Biology, 148 (6). pp. 625-638.

Owida, HA, De Las Heras Ruiz, T, Dhillon, A, Yang, Y ORCID: https://orcid.org/0000-0002-1362-6040 and Kuiper, NJ (2017) Co-culture of chondrons and mesenchymal stromal cells reduces the loss of collagen VI and improves extracellular matrix production. Histochemistry and Cell Biology, 148 (6). pp. 625-638.

Oxley, C, Edge, L, Chubsey, R, Critchlow, C, Satchi, D and Butler, R (2017) Echocardiographic versus cardiac catheterisation derived measures of right heart pressures: a retrospective analysis from the University Hospitals of North Midlands. In: ..

P

Paterson, K, Kasza, J, Hunter, D, Menz, H, Peat, GM ORCID: https://orcid.org/0000-0002-9008-0184 and Bennell, K (2017) The relationship between foot and ankle symptoms and risk of developing knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthritis and Cartilage, 25 (5). pp. 639-646.

Pickard, MR, Adams, CF and Chari, DM (2017) Magnetic Nanoparticle-Mediated Gene Delivery to Two- and Three-Dimensional Neural Stem Cell Cultures: Magnet-Assisted Transfection and Multifection Approaches to Enhance Outcomes. In: Current Protocols in Stem Cell Biology. Wiley, 2D.19.1 - 2D.19.16.

Price, Joshua Colm Felician Aeddan (2017) The development and validation of a hydrostatic pressure bioreactor for applications in bone tissue engineering. Doctoral thesis, Keele University.

R

Rashid, M, Ayyaz Ul Haq, M, Kwok, C, Wong, C, Nolan, J and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Hand dysfunction after transradial artery catheterization for coronary procedures. World Journal of Cardiology, 9 (7). pp. 609-619.

Rashid, M, Kwok, CS, Gale, CP, Doherty, P, Olier, I, Sperrin, M, Kontopanetis, E, Peat, G ORCID: https://orcid.org/0000-0002-9008-0184 and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Impact of Co-morbid burden on mortality in patients with coronary heart disease, heart failure and cerebrovascular accident: a systematic review and meta-analysis. European Heart Journal - Quality of Care and Clinical Outcomes, 3 (1). pp. 20-36.

Rawlins, J, Ludman, PF, O'Neill, D, Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890, de Belder, M, Redwood, S, Banning, A, Whittaker, A and Curzen, N (2017) Variation in emergency percutaneous coronary intervention in ventilated patients in the UK: insights from a national database. Cardiovascular Revascularization Medicine, 18 (4). pp. 250-254.

Richardson, CL, Frisher, M, Johal, J, Jenkins, D and Chapman, S (2017) A retrospective cohort study into the relationship between oral corticosteroids and the incidence of glaucoma and cataracts in COPD patients. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 26. 17 - 17.

Richardson, JB, Wright, KT, Wales, J, Kuiper, JH, McCarthy, HS, Gallacher, P, Harrison, PE and Roberts, S (2017) Efficacy and safety of autologous cell therapies for knee cartilage defects (autologous stem cells, chondrocytes or the two): randomized controlled trial design. Regenerative Medicine, 12 (5). pp. 493-501.

Roach, P and Smith, ME (2017) Saudi to Staffs: learning experiences from Saudi Arabian students’ biomedical research visits to Keele University 2011 to 2016. Journal of Academic Development and Education (8).

Roffe, C ORCID: https://orcid.org/0000-0002-5259-6649, Nevatte, T, Sim, J ORCID: https://orcid.org/0000-0002-1816-1676, Bishop, J, Ives, N, Ferdinand, P, Gray, R and Study Collaborative Group, Stroke Oxygen Study Investigators and the Stroke Oxygen (2017) Effect of Routine Low-Dose Oxygen Supplementation on Death and Disability in Adults With Acute Stroke: The Stroke Oxygen Study Randomized Clinical Trial. JAMA, 318 (12). 1125 - 1135.

Rump, L, Mattey, DL, Kehoe, O and Middleton, J (2017) An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Cytokine, 97. 133 - 140.

S

Sayin, E, Readioff, R, Rodriqiez-Cabello, JC, Elsheikh, A, Turker Baran, E and Hasirci, V (2017) Human adipose derived stem cells are superior to human osteoblasts (HOB) in bone tissue engineering on a collagen-fibroin-ELR blend. Bioactive Materials, 2 (2). 71 - 81.

Schwartz, C, Fischer, M, Mamchaoui, K, Bigot, A, Lok, T, Verdier, C, Duperray, A, Michel, R, Holt, I, Voit, T, Quijano-Roy, S, Bonne, G and Coirault, C (2017) Lamins and nesprin-1 mediate inside-out mechanical coupling in muscle cell precursors through FHOD1. Scientific Reports, 7 (1). 1253 - ?.

Sharma, A, Rees, D, Roberts, S and Kuiper, NJ (2017) A case study: Glycosaminoglycan profiles of autologous chondrocyte implantation (ACI) tissue improves as the tissue matures. The Knee, 24 (1). pp. 149-157.

Sharples, AP (2017) Cellular and Molecular Exercise Physiology: A Historical Perspective for the Discovery of Mechanisms Contributing to Skeletal Muscle Adaptation. Cellular and Molecular Exercise Physiology, 5 (1).

Shestivska, V, Rutter, A, Sule-Suso, J ORCID: https://orcid.org/0000-0003-0598-737X, Smith, D and Spanel, P (2017) Evaluation of peroxidative stress of cancer cells in vitro by real time quantification of volatile aldehydes in culture headspace. Rapid Communications in Mass Spectrometry, 31 (16). pp. 1344-1352.

Siddique, Muhammed Rashid (2017) Improving Leukaemia diagnosis and management with Selected Ion Flow Tube Mass Spectrometry and vibrational spectroscopy techniques. Doctoral thesis, Keele University.

Sirker, A, Kwok, CS ORCID: https://orcid.org/0000-0001-7047-1586 and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Response to letter by Dziewierz et al. on “Influence of access site choice for cardiac catheterization on risk of adverse neurological events: A systematic review and meta- analysis”. American Heart Journal, 181. pp. 107-119.

Sivakumar, Rangasamy (2017) Role of Cyclin D1 polymorphisms and protein over-expression in clinical outcomes of colorectal cancer. Masters thesis, Keele University.

Stalder, R, Potrafke, A, Billstrom, K, Skogby, H, Meinhold, G ORCID: https://orcid.org/0000-0001-8375-8375, Goegele, C and Berberich, T (2017) OH defects in quartz as monitor for igneous, metamorphic, and sedimentary processes. American Mineralogist, 102 (9). 1832 -1842.

T

Tan, Boon Kay (2017) Clinical validation of near-patient assessment of fluid status in dialysis patients. Doctoral thesis, Keele University.

Tang, H, Leung, L, Saturno, G, Viros, A, Smith, D, Di Leva, G, Morrison, E, Niculescu-Duvaz, D, Lopes, F, Johnson, L, Dhomen, N, Springer, C and Marais, R (2017) Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface. Nature Communications, 8. 14909 -?.

Telling, ND, Everett, J, Collingwood, JF, Dobson, J, van der Laan, G, Gallagher, JJ, Wang, J and Hitchcock, AP (2017) Dataset associated with the paper Nanoscale correlation of iron biochemistry with amyloid plaque morphology in Alzheimer’s disease transgenic mouse cortex" to be published in "Cell Chemical Biology". [Dataset] (Unpublished)

Telling, ND, Everett, J, Collingwood, JF, Dobson, J, van der Laan, G, Gallagher, JJ, Wang, J and Hitchcock, AP (2017) Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease. Cell Chemical Biology, 24 (10). pp. 1205-1215.

Thompson, JF, White, S and Chapman, S (2017) Trainee perceptions on the usefulness of Virtual Patients and other support during the pre-registration year. International Journal of Pharmacy Practice, 25 (S1). 33 - 34.

Tickle, Jacqueline Amanda (2017) Engineering neural cells in implantable materials. Doctoral thesis, Keele University.

U

Uche, F, Abed, M, Abdullah, M, Drijfhout, F, McCullagh, J, Claridge, T, Richardson, A ORCID: https://orcid.org/0000-0003-1825-3375 and Li, W (2017) Isolation, identification and anti-cancer activity of minor alkaloids from Triclisia subcordata. Biochemical Pharmacology, 139. p. 112.

Uche, Fidelia Ijeoma (2017) Phytochemical Analysis and Evaluation of Anticancer and Antimalarial Properties of Four Medicinal Plants. Doctoral thesis, Keele University.

W

Ward, R, Carroll, WD, Cunningham, P, Ho, S-A, Jones, M, Lenney, W, Thompson, D and Gilchrist, FJ (2017) Radiation dose from common radiological investigations and cumulative exposure in children with cystic fibrosis: an observational study from a single UK centre. BMJ Open, 7 (8). e017548 - ?.

Weli, H, Akhtar, R, Chang, Z, Li, W, Cooper, J and Yang, Y ORCID: https://orcid.org/0000-0002-1362-6040 (2017) Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 214. pp. 78-85.

Weli, H, Cooper, J and Yang, Y ORCID: https://orcid.org/0000-0002-1362-6040 (2017) Skin advanced glycation content reflects vaginal tissue glycation level in relation to pregnancy. Medical Hypotheses.

Wood, MJA, Talbot, K and Bowerman, M (2017) Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape. Human Molecular Genetics, 26 (R2). R151 - R159.

Wood, Maximilian (2017) An exploration of the effect of the mesenchymal stem cell secretome on pancreatic beta cells. Masters thesis, Keele University.

Wright, KT, Kuiper, JH, Richardson, JB, Gallacher, P and Roberts, S (2017) The absence of detectable ADAMTS-4 (aggrecanase-1) activity in synovial fluid is a predictive indicator of autologous chondrocyte implantation success. American Journal of Sports Medicine, 45 (8). pp. 1806-1814.

Wright, KT, McCarthy, H, Forsyth, NR ORCID: https://orcid.org/0000-0001-5156-4824 and Roberts, S (2017) 283 - Characteristics of human bone marrow mscs are sensitive to mononuclear cell separation technique and oxygen tension. Cytotherapy, 19 (5). S197 - S197.

Wu, P, Haththotuwa, R, Kwok, CS ORCID: https://orcid.org/0000-0001-7047-1586, Babu, A, Kontronias, R, Rushton, C, Zaman, A, Fryer, AA, Kadam, U, Chew-Graham, CA and Mamas, M ORCID: https://orcid.org/0000-0001-9241-8890 (2017) Pre-eclampsia and future cardiovascular health: a systematic review and meta-analysis. Circulation: Cardiovascular Quality and Outcomes, 10 (2).

Z

Zhou, C, Li, C, Zhou, B, Sun, H, Koullourou, V, Holt, I, Puckelwartz, MJ, Warren, DT, Hayward, R, Lin, Z, Zhang, L, Morris, GE, McNally, EM, Shackleton, S, Rao, L, Shanahan, CM and Zhang, Q (2017) Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis. Human Molecular Genetics, 26 (12). 2258 - 2276.

Zhou, Y, Huang, X, Zhao, T, Qiao, M, Zhao, X, Zhao, M, Xu, L, Zhao, Y, Wu, L, Wu, K, Chen, R, Fan, M and Zhu, L (2017) Hypoxia augments LPS-induced inflammation and triggers high altitude cerebral edema in mice. Brain, Behavior, and Immunity, 64. pp. 226-275.

Zong, L, Li, X, Wang, H, Cao, Y, Yin, L, Li, M, Wei, Z, Chen, D, Pu, X and Han, J (2017) Formulation and characterization of biocompatible and stable I.V. itraconazole nanosuspensions stabilized by a new stabilizer polyethylene glycol-poly(β-Benzyl-L-aspartate) (PEG-PBLA). International Journal of Pharmaceutics, 531 (1). pp. 108-117.