Hannah Sinclair
Intravascular imaging-guided intracoronary lithotripsy: First real-world experience
Sinclair, Hannah; Fan, Lampson; Fahy, Eoin; Shahid, Farhan; Ratib, Karim; Nolan, James; Mamas, Mamas; Zaman, Azfar; Ahmed, Javed
Authors
Lampson Fan
Eoin Fahy
Farhan Shahid
Karim Ratib
James Nolan j.nolan@keele.ac.uk
Mamas Mamas m.mamas@keele.ac.uk
Azfar Zaman
Javed Ahmed
Abstract
Background and Aims: Coronary calcification remains a significant challenge for the contemporary interventional cardiologist. We aim to describe the use of intravascular lithotripsy (IVL) in a range of real-world settings. Methods: A retrospective two-center analysis of patients treated with IVL between June 2018 and November 2019. Technical and procedural success, as well as procedural complications and 30-day outcomes (death, myocardial infarction, or repeat target vessel revascularization), was recorded. Results: Sixty-five patients underwent IVL: 80% were male and the mean age was 70.1?±?12.0?years. 54% of patients presented with acute coronary syndrome (ACS) and 68% of patients had intracoronary imaging. Twelve patients required IVL within pre-existing stents, and 12 underwent IVL in the left main stem. All balloons were successfully delivered with 98.5% procedural success. There was a significant gain in MLA post PCI of 261.9 ±?100% following IVL. There were two procedural complications. At 30-day follow-up, there was one death, and one patient required a repeat procedure due to stent underexpansion. Conclusions: In this largest real-world series of imaging-guided IVL for calcified lesions to date, we demonstrate that IVL is deliverable, safe, and effective at calcium modification especially when intracoronary imaging is used.
Journal Article Type | Article |
---|---|
Acceptance Date | Apr 15, 2021 |
Online Publication Date | Aug 9, 2021 |
Publication Date | Sep 1, 2021 |
Publicly Available Date | May 30, 2023 |
Journal | Health Science Reports |
Print ISSN | 2398-8835 |
Publisher | Wiley Open Access |
Volume | 4 |
Issue | 3 |
Article Number | e307 |
DOI | https://doi.org/10.1002/hsr2.307 |
Keywords | General Medicine |
Publisher URL | https://onlinelibrary.wiley.com/doi/10.1002/hsr2.307 |
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