Shamkhani, W, Rashid, M ORCID: https://orcid.org/0000-0001-9725-1583 and Mamas, MA ORCID: https://orcid.org/0000-0001-9241-8890 (2022) COMPLEX, HIGH-RISK BUT INDICATED PERCUTANEOUS CORONARY INTERVENTIONS (CHIP) TYPES AND OUTCOMES AMONG DIFFERENT AGE GROUPS. AN INSIGHT FROM A NATIONAL REGISTRY. Journal of the American College of Cardiology, 79 (9). 855 - 855.

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Abstract

Background: Studies looking at Complex, High-risk but Indicated Percutaneous coronary intervention (CHiP) type and outcomes among the octogenarian are limited. Methods: Data on PCI for stable angina from 1st January 2006 to 31st December 2017 was obtained from the BCIS registry. CHiP cases were identified, categorized according to age into three groups (Group 1: below 65, Group 2: 65-79, and Group 3: age 80 and above years). Multivariable regression analysis was performed to determine adjusted odds of in-hospital outcomes between the groups. Results: Out of 424,290 procedures’ records, 138,831 (33.0%) were CHiP [Group 1: 33.7%; Group 2: 42.9%; Group 3: 23.4%]. The most common variable in Group 3 was prior CABG (15.8%), then severe calcifications (15.5%) and chronic renal failure (11.1%). Whereas in Group,1 it was CTO PCI (49.2%), prior CABG (30.4%) and severe vessel calcifications (21.8%). In Group 2 it was prior CABG (42.9%), PCI to a CTO (32.9%) and severe vessel calcifications (21.8%). Adjusted odds for adverse outcomes were worse in those 65 years and above [Group 2, Mortality aOR 1.7, 95% CI (1.3-2.2); Bleeding aOR 1.3, 95% CI (1.2-1.6); MACCE: aOR 1.2, 95% CI (1.0-1.3), p<0.015) (Group 3: Mortality aOR 2.7, 95%CI (1.9-3.6); Bleeding: aOR 1.5, 95% CI (1.2-1.7); MACCE: aOR 1.3, 95% CI (1.2-1.5). Conclusion: There were significant differences in CHiP types between the age groups. Despite a lower cardiometabolic burden among the octogenarian, their CHiP outcomes were worse than the younger patients.

Item Type: Article
Additional Information: The final version of this article and all relevant information related to it, including copyrights, can be found on the publisher website.
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC666 Diseases of the circulatory (Cardiovascular) system
Divisions: Faculty of Medicine and Health Sciences > School of Medicine
Related URLs:
Depositing User: Symplectic
Date Deposited: 30 May 2022 14:16
Last Modified: 30 May 2022 14:16
URI: https://eprints.keele.ac.uk/id/eprint/10977

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