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COMPLEX, HIGH-RISK BUT INDICATED PERCUTANEOUS CORONARY INTERVENTIONS (CHIP) TYPES AND OUTCOMES AMONG DIFFERENT AGE GROUPS. AN INSIGHT FROM A NATIONAL REGISTRY

Abstract

Background: Studies looking at Complex, High-risk but Indicated Percutaneous coronary intervention (CHiP) type and outcomes among the octogenarian are limited. Methods: Data on PCI for stable angina from 1st January 2006 to 31st December 2017 was obtained from the BCIS registry. CHiP cases were identified, categorized according to age into three groups (Group 1: below 65, Group 2: 65-79, and Group 3: age 80 and above years). Multivariable regression analysis was performed to determine adjusted odds of in-hospital outcomes between the groups. Results: Out of 424,290 procedures’ records, 138,831 (33.0%) were CHiP [Group 1: 33.7%; Group 2: 42.9%; Group 3: 23.4%]. The most common variable in Group 3 was prior CABG (15.8%), then severe calcifications (15.5%) and chronic renal failure (11.1%). Whereas in Group,1 it was CTO PCI (49.2%), prior CABG (30.4%) and severe vessel calcifications (21.8%). In Group 2 it was prior CABG (42.9%), PCI to a CTO (32.9%) and severe vessel calcifications (21.8%). Adjusted odds for adverse outcomes were worse in those 65 years and above [Group 2, Mortality aOR 1.7, 95% CI (1.3-2.2); Bleeding aOR 1.3, 95% CI (1.2-1.6); MACCE: aOR 1.2, 95% CI (1.0-1.3), p<0.015) (Group 3: Mortality aOR 2.7, 95%CI (1.9-3.6); Bleeding: aOR 1.5, 95% CI (1.2-1.7); MACCE: aOR 1.3, 95% CI (1.2-1.5). Conclusion: There were significant differences in CHiP types between the age groups. Despite a lower cardiometabolic burden among the octogenarian, their CHiP outcomes were worse than the younger patients.

Acceptance Date Apr 1, 2022
Publication Date Mar 8, 2022
Journal Journal of the American College of Cardiology
Print ISSN 0735-1097
Publisher Elsevier
Pages 855 - 855
DOI https://doi.org/10.1016/s0735-1097%2822%2901846-0
Publisher URL https://www.jacc.org/doi/10.1016/S0735-1097%2822%2901846-0