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Common and unique associated factors for medically unexplained chronic widespread pain and chronic fatigue.

McBeth, J.; Tomenson, B.; Chew-Graham, C.A.; Macfarlane, G.J.; Jackson, J.; Littlewood, A.; Creed, F.H.

Common and unique associated factors for medically unexplained chronic widespread pain and chronic fatigue. Thumbnail


Authors

J. McBeth

B. Tomenson

G.J. Macfarlane

J. Jackson

A. Littlewood

F.H. Creed



Abstract

OBJECTIVE: Chronic widespread pain and chronic fatigue share common associated factors but these associations may be explained by the presence of concurrent depression and anxiety. METHODS: We mailed questionnaires to a randomly selected sample of people in the UK to identify participants with chronic widespread pain (ACR 1990 definition) and those with chronic fatigue. The questionnaire assessed sociodemographic factors, health status, healthcare use, childhood factors, adult attachment, and psychological stress including anxiety and depression. To identify persons with unexplained chronic widespread pain or unexplained chronic fatigue; we examined participant's medical records to exclude medical illness that might cause these symptoms. RESULTS: Of 1443 participants (58.0% response rate) medical records of 990 were examined. 9.4% (N=93) had unexplained chronic widespread pain and 12.6% (N=125) had unexplained chronic fatigue. Marital status, childhood psychological abuse, recent threatening experiences and other somatic symptoms were commonly associated with both widespread pain and fatigue. No common effect was found for few years of education and current medical illnesses (more strongly associated with chronic widespread pain) or recent illness in a close relative, neuroticism, depression and anxiety scores (more strongly associated with chronic fatigue). Putative associated factors with a common effect were associated with unexplained chronic widespread pain or unexplained chronic fatigue only when there was concurrent anxiety and/or depression. DISCUSSION: This study suggests that the associated factors for chronic widespread pain and chronic fatigue need to be studied in conjunction with concurrent depression/anxiety. Clinicians should be aware of the importance of concurrent anxiety or depression.

Acceptance Date Oct 15, 2015
Publication Date Oct 19, 2015
Publicly Available Date Mar 29, 2024
Journal Journal of Psychosomatic Research
Print ISSN 0022-3999
Publisher Elsevier
Pages 484 - 491
DOI https://doi.org/10.1016/j.jpsychores.2015.10.004
Keywords chronic fatigue; epidemiology; fibromyalgia; functional somatic syndromes; medically unexplained symptoms; population based
Publisher URL http://www.sciencedirect.com/science/article/pii/S0022399915005565

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