Chemical and enzymatic synthesis of the alginate sugar nucleotide building block: GDP-d-mannuronic acid

Beswick, Laura; Ahmadipour, Sanaz; Dolan, Jonathan P.; Rejzek, Martin; Field, Robert A.; Miller, Gavin J.

doi:10.1016/j.carres.2019.107819

Chemical and enzymatic synthesis of the alginate sugar nucleotide building block: GDP-d-mannuronic acid

Beswick, Laura; Ahmadipour, Sanaz; Dolan, Jonathan P.; Rejzek, Martin; Field, Robert A.; Miller, Gavin J.

Authors

Laura Beswick

Sanaz Ahmadipour

Jonathan Dolan j.dolan@keele.ac.uk

Martin Rejzek

Robert A. Field

Gavin Miller g.j.miller@keele.ac.uk

Abstract

Highlights

Sugarnucleotide synthesis.

Chemical and enzymatic access to GDP-d-ManA.

Evaluation of protected and free uronate 1-phosphates for pyrophosphorylation.

Journal Article Type	Article
Acceptance Date	Sep 16, 2019
Online Publication Date	Sep 17, 2019
Publication Date	Nov 1, 2019
Publicly Available Date	May 26, 2023
Journal	Carbohydrate Research
Print ISSN	0008-6215
Publisher	Elsevier
Peer Reviewed	Peer Reviewed
Volume	485
Issue	1
Pages	107819 -107819
DOI	https://doi.org/10.1016/j.carres.2019.107819
Keywords	Sugar nucleotide; Glycosyl-1-phosphate; Mannuronate; Pyrophosphorylation; Alginate
Publisher URL	http://www.sciencedirect.com/science/article/pii/S0008621519304458