Maarabouni, MM ORCID: https://orcid.org/0000-0001-8324-1325 and Williams, GT (2006) The antiapoptotic RBM5/LUCA-15/H37 gene and its role in apoptosis and human cancer: research update. Scientific World Journal, 6. 1705 - 1712.

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Abstract

The candidate tumour-suppressor gene, LUCA-15/RBM5/H37, maps to the lung cancer tumour-suppressor locus 3p21.3. The LUCA-15 gene locus encodes at least four alternatively spliced transcripts that have been shown to function as regulators of apoptosis, a fact which may have major significance in tumour regulation. This review highlights recent evidence that further implicates the LUCA-15 locus in the control of apoptosis and cell proliferation, and focuses on the observations that confirm the tumour-suppressor activity of this gene.

Item Type: Article
Additional Information: The final version of this article with all relevant information can be found at; https://www.hindawi.com/journals/tswj/2006/819835/
Uncontrolled Keywords: Apoptosis (D017209), Cell Cycle Proteins (D018797), Cell Proliferation (D049109), DNA-Binding Proteins (D004268), Gene Expression Regulation, Neoplastic (D015972), Genes, Tumor Suppressor (D016147), Humans (D006801), Lung Neoplasms (D008175), RNA-Binding Proteins (D016601), Tumor Suppressor Proteins (D025521)
Subjects: Q Science > Q Science (General)
R Medicine > R Medicine (General)
R Medicine > R Medicine (General) > R735 Medical education. Medical schools. Research
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Faculty of Natural Sciences > School of Life Sciences
Related URLs:
Depositing User: Symplectic
Date Deposited: 18 May 2020 11:09
Last Modified: 18 May 2020 11:09
URI: https://eprints.keele.ac.uk/id/eprint/7965

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