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Maarabouni, MM ORCID: https://orcid.org/0000-0001-8324-1325 and Williams, GT
(2006)
The antiapoptotic RBM5/LUCA-15/H37 gene and its role in apoptosis and human cancer: research update.
Scientific World Journal, 6.
1705 - 1712.
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The antiapoptotic RBM5LUCA-15H37 gene and its role in apoptosis and human cancer research update.pdf - Published Version Download (138kB) | Preview |
Abstract
The candidate tumour-suppressor gene, LUCA-15/RBM5/H37, maps to the lung cancer tumour-suppressor locus 3p21.3. The LUCA-15 gene locus encodes at least four alternatively spliced transcripts that have been shown to function as regulators of apoptosis, a fact which may have major significance in tumour regulation. This review highlights recent evidence that further implicates the LUCA-15 locus in the control of apoptosis and cell proliferation, and focuses on the observations that confirm the tumour-suppressor activity of this gene.
Item Type: | Article |
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Additional Information: | The final version of this article with all relevant information can be found at; https://www.hindawi.com/journals/tswj/2006/819835/ |
Uncontrolled Keywords: | Apoptosis (D017209), Cell Cycle Proteins (D018797), Cell Proliferation (D049109), DNA-Binding Proteins (D004268), Gene Expression Regulation, Neoplastic (D015972), Genes, Tumor Suppressor (D016147), Humans (D006801), Lung Neoplasms (D008175), RNA-Binding Proteins (D016601), Tumor Suppressor Proteins (D025521) |
Subjects: | Q Science > Q Science (General) R Medicine > R Medicine (General) R Medicine > R Medicine (General) > R735 Medical education. Medical schools. Research R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
Divisions: | Faculty of Natural Sciences > School of Life Sciences |
Related URLs: | |
Depositing User: | Symplectic |
Date Deposited: | 18 May 2020 11:09 |
Last Modified: | 18 May 2020 11:09 |
URI: | https://eprints.keele.ac.uk/id/eprint/7965 |
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