Shi, R, Cai, Y, Qin, R, Yang, Y ORCID: https://orcid.org/0000-0002-4292-627X and Yu, D ORCID: https://orcid.org/0000-0002-8449-7725 (2020) Dose-response association between physical activity and clustering of modifiable cardiovascular risk factors among 26,093 Chinese adults. BMC Cardiovascular Disorders, 20 (1).

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Abstract

Background
There is uncertain evidence in the dose-response association between overall physical activity levels and clustering of cardiovascular diseases modifiable risk factors (CVDMRF) in Chinese adults. This study examined the hypothesis whether inverse dose-response association between overall physical activity levels and clustering of CVDMRF in Chinese adults exist.

Methods
Twenty-six thousand ninety-three Chinese adult participants were recruited by two independent surveys in Nanjing and Hefei during 2011 to 2013, from random selected households provided smoking, glucose, lipids, anthropometric, and blood pressure measurements. Logistic regression model was applied to examine the dose-response association between overall physical activity (measured by metabolic equivalent task (MET)- minutes per week) and having ≥1, ≥2, and ≥ 3 CVDMRF (dyslipidemia, hypertension, diabetes, cigarette smoking, and overweight).

Results
An inverse linear dose-response relationship between physical activity and clustering of CVDMRF was identified, as increased physical activity levels are associated with lower odds of having clustering of CVDMRF. The adjusted odds ratio (95% confidence interval) of having ≥1, ≥2, and ≥ 3 CVRF for moderate physical activity group and high physical activity group was 0.88 (0.79 to 0.98) and 0.88 (0.79 to 0.99), 0.85 (0.78 to 0.92) and 0.85 (0.78 to 0.92), 0.84 (0.76 to 0.91) and 0.81 (0.74 to 0.89), respectively, with low physical activity as reference group.

Conclusions
Among Chinese adults, physical activity level inversely associates with clustering of CVDMRF, especially in those aged 35–54 years. Health promotion including improve physical activity should be advocated. The potential role of physical activity in the clustering of CVDMRF warrants further validation.

Item Type: Article
Additional Information: Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
Uncontrolled Keywords: Physical activity, Cardiovascular diseases, Cardiovascular risk factor
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RC Internal medicine > RC666 Diseases of the circulatory (Cardiovascular) system
Divisions: Faculty of Medicine and Health Sciences > School of Primary, Community and Social Care
Depositing User: Symplectic
Date Deposited: 31 Jul 2020 11:33
Last Modified: 20 Aug 2020 09:51
URI: https://eprints.keele.ac.uk/id/eprint/8463

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