Sidi, M, Ugwu, AC, England, A ORCID: https://orcid.org/0000-0001-6333-7776, Manafa, PO, Dambatta, AH, Zira, JD, Saleh, MK, Ya'u, A and Mansur, U (2021) Renal doppler indices and their correlation with laboratory indices of human immunodeficiency virus sero-positive adult individuals. Radiography, 27 (4). pp. 1014-1020.

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Abstract

Introduction
Renal Doppler resistive index (RI) and pulsatility index (PI) values are potentially more sensitive at detecting renal abnormalities when compared to standard laboratory indices in patients with HIV/AIDS. To the best of our knowledge, there are no published research articles on renal Doppler indices and their correlation with laboratory indices of HIV sero-positive adult individuals. This study aimed to assess the renal function of HIV-sero-positive adults using RI and PI, and correlating these indices against laboratory values.

Methods
A prospective cross-sectional study was conducted from July 2019 to April 2020. A purposive sampling method was employed and included 396 HIV sero-positive adult individuals. Sampling for the renal RI and PI was performed at the level of the inter-lober arteries, in between the medullary pyramids. An RI value above 0.70 and a PI value above 1.56 were consider abnormal. Serum creatine and urea together with evidence of proteinuria were recorded at the time of scanning.

Results
Forty-three (10.9%) men had an abnormal RI, 32 (8.1%) had abnormal PI, five (2.5%) had abnormal creatinine, two (1%) abnormal urea and eight (4.1%) with proteinuria. In women, 29 (7.3%) had abnormal RI, 22 (5.6%) abnormal PI, four (2%) abnormal creatinine and urea and six (3%) had proteinuria. There was a statistically significant weak positive correlation between RI and PI and serum creatinine and urea (r > 0.2, P < 0.05).

Conclusion
The proportion of patients with abnormal RI and PI was higher than the proportion of participants with abnormal serum urea, creatinine and proteinuria. Renal Doppler indices could be used be used in the early assessment of renal function in HIV sero-positive adults individuals.

Item Type: Article
Additional Information: The final version of this accepted manuscript is available direct from the publishers at https://www.radiographyonline.com/article/S1078-8174(21)00031-6/fulltext#secsectitle0010
Uncontrolled Keywords: Renal Doppler; Indices; HIV/AIDS
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC902 Nephrology
Depositing User: Symplectic
Date Deposited: 23 Apr 2021 10:44
Last Modified: 16 Apr 2022 01:30
URI: https://eprints.keele.ac.uk/id/eprint/9398

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