Keele Research Repository
Explore the Repository
Ponts, N, Yang, J, Chung, DW, Prudhomme, J, Girke, T, Horrocks, P ORCID: https://orcid.org/0000-0003-3981-0732 and Le Roch, KG
(2008)
Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence.
PLoS One, 3 (6).
e2386 - ?.
|
Text
Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence..pdf Download (1MB) | Preview |
Abstract
Reversible modification of proteins through the attachment of ubiquitin or ubiquitin-like modifiers is an essential post-translational regulatory mechanism in eukaryotes. The conjugation of ubiquitin or ubiquitin-like proteins has been demonstrated to play roles in growth, adaptation and homeostasis in all eukaryotes, with perturbation of ubiquitin-mediated systems associated with the pathogenesis of many human diseases, including cancer and neurodegenerative disorders.
Item Type: | Article |
---|---|
Uncontrolled Keywords: | Apicomplexa, Plasmodium, Protein domains, Toxoplasma gondii, Ligases, Ubiquitin ligases, Cell cycle and cell division, Conjugated proteins |
Subjects: | Q Science > QH Natural history > QH301 Biology |
Divisions: | Faculty of Natural Sciences > School of Life Sciences |
Related URLs: | |
Depositing User: | Symplectic |
Date Deposited: | 26 Nov 2014 13:16 |
Last Modified: | 23 Aug 2018 13:57 |
URI: | https://eprints.keele.ac.uk/id/eprint/99 |
Actions (login required)
![]() |
View Item |