Wrigley, AJ, Wilkinson, S and Appleby, JB (2015) Mitochondrial Replacement: ethics and identity. Bioethics, 29 (9). pp. 631-638. ISSN 1467-8519

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Mitochondrial replacement techniques (MRTs) have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer (PNT) and Maternal Spindle Transfer (MST). It examines how questions of identity impact on the ethical evaluation of each technique and argues that there is an important difference between the two. PNT, it is argued, is a form of therapy based on embryo modification while MST is, instead, an instance of selective reproduction. The article's main ethical conclusion is that, in some circumstances, there is a stronger obligation to use PNT than MST.

Item Type: Article
Uncontrolled Keywords: mitochondrial replacement, genetics, identity, ethics, reproductive technology
Subjects: K Law > K Law (General)
Divisions: Faculty of Humanities and Social Sciences > School of Law
Depositing User: Symplectic
Date Deposited: 19 Oct 2015 08:53
Last Modified: 23 Apr 2019 11:13
URI: https://eprints.keele.ac.uk/id/eprint/1030

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