Haugen, IK, Felson, D, Abhishek, A, Berenbaum, F, Edwards, JJ, Herrero Beaumont, G, Hermann-Eriksen, M, Hill, CL, Ishimori, M, Jonsson, H, Karjalainen, T, Leung, YY, Maheu, E, Mallen, CD, Moe, RH, Ramonda, R, Ritschl, V, Stamm, TA, Szekanecz, Z, van der Giesen, FJ, Ritt, MJPF, Wittoek, R, Kjeken, I, Osteras, N, van de Stadt, LA, Englund, M, Dziedzic, KS, Marshall, M, Bierma-Zeinstra, S, Hansen, P, Greibrokk, E, Smeets, W and Kloppenburg, M (2022) Development of radiographic classification criteria for hand osteoarthritis: a methodological report (Phase 2). RMD Open, 8 (1). e002024 - e002024. ISSN 2056-5933

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Objectives In Phase 1 of developing new hand osteoarthritis (OA) classification criteria, features associated with hand OA were identified in a population with hand complaints. Radiographic findings could better discriminate patients with hand OA and controls than clinical examination findings. The objective of Phase 2 was to achieve consensus on the features and their weights to be included in three radiographic criteria sets of overall hand OA, interphalangeal OA and thumb base OA. Methods Multidisciplinary, international expert panels were convened. Patient vignettes were used to identify important features consistent with hand OA. A consensus-based decision analysis approach implemented using 1000minds software was applied to identify the most important features and their relative importance influencing the likelihood of symptoms being due to hand OA. Analyses were repeated for interphalangeal and thumb base OA. The reliability and validity of the proposed criteria sets were tested. Results The experts agreed that the criteria sets should be applied in a population with pain, aching or stiffness in hand joint(s) not explained by another disease or acute injury. In this setting, five additional criteria were considered important: age, morning stiffness, radiographic osteophytes, radiographic joint space narrowing and concordance between symptoms and radiographic findings. The reliability and validity were very good. Conclusion Radiographic features were considered critical when determining whether a patient had symptoms due to hand OA. The consensus-based decision analysis approach in Phase 2 complemented the data-driven results from Phase 1, which will form the basis of the final classification criteria sets.

Item Type: Article
Additional Information: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
Uncontrolled Keywords: osteoarthritis; outcome assessment; health care; epidemiology
Subjects: R Medicine > RC Internal medicine > RC925 Diseases of the musculoskeletal system
R Medicine > RM Therapeutics. Pharmacology > Physical medicine. Physical therapy. Including massage, exercise, occupational therapy, hydrotherapy, phototherapy, radiotherapy, thermotherapy, electrotherapy
Depositing User: Symplectic
Date Deposited: 10 Feb 2022 13:12
Last Modified: 13 Apr 2022 13:35
URI: https://eprints.keele.ac.uk/id/eprint/10609

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