Peña-Solórzano, CA, Albrecht, DW, Bassed, RB, Gillam, J, Harris, PC and Dimmock, MR (2020) Semi-supervised labelling of the femur in a whole-body post-mortem CT database using deep learning. Computers in Biology and Medicine, 122 (103797). -. ISSN 0010-4825

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A deep learning pipeline was developed and used to localize and classify a variety of implants in the femur contained in whole-body post-mortem computed tomography (PMCT) scans. The results provide a proof-of-principle approach for labelling content not described in medical/autopsy reports. The pipeline, which incorporated residual networks and an autoencoder, was trained and tested using n = 450 full-body PMCT scans. For the localization component, Dice scores of 0.99, 0.96, and 0.98 and mean absolute errors of 3.2, 7.1, and 4.2 mm were obtained in the axial, coronal, and sagittal views, respectively. A regression analysis found the orientation of the implant to the scanner axis and also the relative positioning of extremities to be statistically significant factors. For the classification component, test cases were properly labelled as nail (N+), hip replacement (H+), knee replacement (K+) or without-implant (I-) with an accuracy >97%. The recall for I- and H+ cases was 1.00, but fell to 0.82 and 0.65 for cases with K+ and N+. This semi-automatic approach provides a generalized structure for image-based labelling of features, without requiring time-consuming segmentation.

Item Type: Article
Additional Information: The final version of this article and all information related to it, including copyrights, can be found on the publisher website.
Subjects: Q Science > QA Mathematics
T Technology > T Technology (General)
Divisions: Faculty of Medicine and Health Sciences > School of Allied Health Professions
Related URLs:
Depositing User: Symplectic
Date Deposited: 27 Jul 2022 08:55
Last Modified: 27 Jul 2022 08:55

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