Rotherham, M, Nahar, T, Broomhall, TJ, Telling, ND and El Haj, AJ (2022) Remote magnetic actuation of cell signalling for tissue engineering. Current Opinion in Biomedical Engineering, 24 (100410). ISSN 2468-4511

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Magnetic nanoparticles (MNP) are extremely versatile tools in bioengineering and medicine with diverse uses ranging from magnetic resonance contrast agents to drug delivery vehicles. Recently, MNP have been adapted to target and regulate cell signalling pathways for control of cell behaviour. This approach has been applied to stem and progenitor cells to orchestrate tissue development in tissue engineering. This review introduces the bio-functionalisation mechanisms for MNP and highlights the recent advances in MNP-mediated cell signalling activation. We also explore how the application of this technology has novel uses for stem cell control in the context of tissue engineering and regenerative medicine.

Item Type: Article
Additional Information: © 2022 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (
Subjects: R Medicine > R Medicine (General) > R735 Medical education. Medical schools. Research
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RM Therapeutics. Pharmacology > Physical medicine. Physical therapy. Including massage, exercise, occupational therapy, hydrotherapy, phototherapy, radiotherapy, thermotherapy, electrotherapy
Divisions: Faculty of Medicine and Health Sciences > School of Pharmacy and Bioengineering
Related URLs:
Depositing User: Symplectic
Date Deposited: 10 Nov 2022 13:32
Last Modified: 10 Nov 2022 13:32

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