Littlejohns, TJ, Holliday, J, Gibson, LM, Garratt, S, Oesingmann, N, Alfaro-Almagro, F, Bell, JD, Boultwood, C, Collins, R, Conroy, MC, Crabtree, N, Doherty, N, Frangi, AF, Harvey, NC, Leeson, P, Miller, KL, Neubauer, S, Petersen, SE, Sellors, J, Sheard, S, Smith, SM, Sudlow, CLM, Matthews, PM, Allen, NE and Kariki, E (2020) The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions. Nature Communications, 11 (1). ISSN 2041-1723

[thumbnail of s41467-020-15948-9.pdf]
s41467-020-15948-9.pdf - Published Version

Download (811kB) | Preview


<jats:title>Abstract</jats:title><jats:p>UK Biobank is a population-based cohort of half a million participants aged 40–69 years recruited between 2006 and 2010. In 2014, UK Biobank started the world’s largest multi-modal imaging study, with the aim of re-inviting 100,000 participants to undergo brain, cardiac and abdominal magnetic resonance imaging, dual-energy X-ray absorptiometry and carotid ultrasound. The combination of large-scale multi-modal imaging with extensive phenotypic and genetic data offers an unprecedented resource for scientists to conduct health-related research. This article provides an in-depth overview of the imaging enhancement, including the data collected, how it is managed and processed, and future directions.</jats:p>

Item Type: Article
Additional Information: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit
Subjects: R Medicine > R Medicine (General)
R Medicine > R Medicine (General) > R735 Medical education. Medical schools. Research
Divisions: Faculty of Medicine and Health Sciences > School of Medicine
Depositing User: Symplectic
Date Deposited: 26 Apr 2023 09:42
Last Modified: 26 Apr 2023 09:42

Actions (login required)

View Item
View Item