Clarson, LE, Hider, SL, Belcher, J, Roddy, E and Mallen, CD (2017) Factors Influencing Allopurinol Initiation in Primary Care. Ann Fam Med, 15 (6). 557 - 560.

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Despite guidance on appropriate initiation, urate-lowering therapy is prescribed for only a minority of patients with gout. Electronic health records for 8,142 patients with gout were used to investigate the effect of age, sex, comorbidities, number of consultations, and meeting internationally agreed eligibility criteria on time to allopurinol initiation. Time to first prescription was modeled using multilevel Cox proportional hazards regression. Allopurinol initiation was positively associated with meeting eligibility criteria at diagnosis of gout, but negatively associated with becoming eligible after diagnosis. Managing gout as a chronic disease, with regular reviews to discuss allopurinol treatment, may reduce barriers to treatment.

Item Type: Article
Uncontrolled Keywords: allopurinol; gout; primary care
Subjects: R Medicine > RC Internal medicine > RC927 Rheumatism
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine and Health Sciences > School of Medicine
Related URLs:
Depositing User: Symplectic
Date Deposited: 10 May 2023 14:55
Last Modified: 10 May 2023 14:55

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