Dejaco, C, Singh, YP, Perel, P, Hutchings, A, Camellino, D, Mackie, S, Abril, A, Bachta, A, Balint, P, Barraclough, K, Bianconi, L, Buttgereit, F, Carsons, S, Ching, D, Cid, M, Cimmino, M, Diamantopoulos, A, Docken, W, Duftner, C, Fashanu, B, Gilbert, K, Hildreth, P, Hollywood, J, Jayne, D, Lima, M, Maharaj, A, Mallen, C, Martinez-Taboada, V, Maz, M, Merry, S, Miller, J, Mori, S, Neill, L, Nordborg, E, Nott, J, Padbury, H, Pease, C, Salvarani, C, Schirmer, M, Schmidt, W, Spiera, R, Tronnier, D, Wagner, A, Whitlock, M, Matteson, EL, Dasgupta, B, Against Rheumatism, European League and of Rheumatology, American College (2015) 2015 recommendations for the management of polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative. Arthritis Rheumatol, 67 (10). 2569 - 2580. ISSN Arthritis & Rheumatology

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Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients' and clinicians' values and preferences, and resource use. Eight overarching principles and nine specific recommendations were developed covering several aspects of PMR, including basic and follow-up investigations of patients under treatment, risk factor assessment, medical access for patients and specialist referral, treatment strategies such as initial glucocorticoid (GC) doses and subsequent tapering regimens, use of intramuscular GCs and disease modifying anti-rheumatic drugs (DMARDs), as well as the roles of non-steroidal anti-rheumatic drugs and non-pharmacological interventions. These recommendations will inform primary, secondary and tertiary care physicians about an international consensus on the management of PMR. These recommendations should serve to inform clinicians about best practices in the care of patients with PMR.

Item Type: Article
Additional Information: The final version of this article and all relevant information related to it, including copyrights, can be found on the publisher website.
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine and Health Sciences > School of Medicine
Related URLs:
Depositing User: Symplectic
Date Deposited: 11 May 2023 12:24
Last Modified: 11 May 2023 12:24

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