Skip to main content

Research Repository

Advanced Search

Status of selected ion flow tube MS: accomplishments and challenges in breath analysis and other areas

Status of selected ion flow tube MS: accomplishments and challenges in breath analysis and other areas Thumbnail


Abstract

This article reflects our observations of recent accomplishments made using selected ion flow tube MS (SIFT-MS). Only brief descriptions are given of SIFT-MS as an analytical method and of the recent extensions to the underpinning analytical ion chemistry required to realize more robust analyses. The challenge of breath analysis is given special attention because, when achieved, it renders analysis of other air media relatively straightforward. Brief overviews are given of recent SIFT-MS breath analyses by leading research groups, noting the desirability of detection and quantification of single volatile biomarkers rather than reliance on statistical analyses, if breath analysis is to be accepted into clinical practice. A 'strengths, weaknesses, opportunities and threats' analysis of SIFT-MS is made, which should help to increase its utility for trace gas analysis.

Acceptance Date Apr 12, 2016
Publication Date May 23, 2016
Publicly Available Date Mar 28, 2024
Journal Bioanalysis
Print ISSN 1757-6180
Publisher Future Science
Pages 1183 -1201
DOI https://doi.org/10.4155/bio-2016-0038
Keywords SIFT-MS, SWOT analysis, breath analysis, cancer, cystic fibrosis, metabolites, real-time analysis, selected ion flow tube MS, small molecules, trace gas analysis, volatile organic compounds
Publisher URL http://dx.doi.org/10.4155/bio-2016-0038

Files




Downloadable Citations