Sally Roberts
Ageing in the musculoskeletal system
Roberts, Sally; Colombier, Pauline; Sowman, Aneka; Mennan, Claire; Rölfing, Jan H D; Guicheux, Jérôme; Edwards, James R
Authors
Pauline Colombier
Aneka Sowman
Claire Mennan c.mennan@keele.ac.uk
Jan H D Rölfing
Jérôme Guicheux
James R Edwards
Abstract
The extent of ageing in the musculoskeletal system during the life course affects the quality and length of life. Loss of bone, degraded articular cartilage, and degenerate, narrowed intervertebral discs are primary features of an ageing skeleton, and together they contribute to pain and loss of mobility. This review covers the cellular constituents that make up some key components of the musculoskeletal system and summarizes discussion from the 2015 Aarhus Regenerative Orthopaedic Symposium (AROS) (Regeneration in the Ageing Population) about how each particular cell type alters within the ageing skeletal microenvironment.
Journal Article Type | Article |
---|---|
Acceptance Date | Jun 14, 2016 |
Online Publication Date | Dec 16, 2016 |
Publication Date | Oct 17, 2016 |
Publicly Available Date | Mar 28, 2024 |
Journal | Acta Orthopaedica |
Print ISSN | 1745-3674 |
Publisher | Informa Healthcare |
Peer Reviewed | Peer Reviewed |
Volume | 87 |
Issue | S363 |
Pages | 15- 25 |
DOI | https://doi.org/10.1080/17453674.2016.1244750 |
Publisher URL | https://doi.org/10.1080/17453674.2016.1244750 |
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