George Peat
Improving the transparency of prognosis research: the role of reporting, data sharing, registration, and protocols
Peat, George; Riley, Richard D.; Croft, Peter; Morley, Katherine I.; Kyzas, Panayiotis A.; Moons, Karel G.M.; Perel, Pablo; Steyerberg, Ewout W.; Schroter, Sara; Altman, Douglas G.; Hemingway, Harry; van der Windt, Danielle
Authors
Richard D. Riley
Peter Croft
Katherine I. Morley
Panayiotis A. Kyzas
Karel G.M. Moons
Pablo Perel
Ewout W. Steyerberg
Sara Schroter
Douglas G. Altman
Harry Hemingway
Danielle Van Der Windt d.van.der.windt@keele.ac.uk
Abstract
Prognosis research is concerned with predicting outcomes to make health care more effective. It has a crucial role to play in clinical and policy decision-making. The quality of much prognosis research is poor, evidenced by incomplete reporting, poor data sharing, incomplete registrations, and absent study protocols. Initiatives to improve transparency in trials include reporting guidelines, data pooling, registers, and journal requirements for protocols. Prognosis research could be transformed by similar initiatives. Routine registration of all prognostic studies, linked to an accessible study protocol using agreed reporting guidelines, would improve transparency and promote data sharing. Concern about applying transparency methods to observational research could be resolved by flexibility to update date-stamped protocols during prognosis studies.
Journal Article Type | Article |
---|---|
Acceptance Date | Jul 8, 2014 |
Publication Date | Jul 8, 2014 |
Journal | PLoS Medicine |
Print ISSN | 1549-1277 |
Publisher | Public Library of Science |
Pages | e1001671 -? |
DOI | https://doi.org/10.1371/journal.pmed.1001671 |
Keywords | biomedical research, clinical protocols, humans, information dissemination, prognosis, vital statistics |
Publisher URL | http://dx.doi.org/10.1371/journal.pmed.1001671 |
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