Urban, JPG and Roberts, S (2003) Degeneration of the intervertebral disc. Arthritis Research & Therapy, 5 (3). 120 -130. ISSN 1478-6354

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The intervertebral disc is a cartilaginous structure that resembles articular cartilage in its biochemistry, but morphologically it is clearly different. It shows degenerative and ageing changes earlier than does any other connective tissue in the body. It is believed to be important clinically because there is an association of disc degeneration with back pain. Current treatments are predominantly conservative or, less commonly, surgical; in many cases there is no clear diagnosis and therapy is considered inadequate. New developments, such as genetic and biological approaches, may allow better diagnosis and treatments in the future.

Item Type: Article
Additional Information: This is the final published version of the article (version of record). It first appeared online via BioMed Central at http://dx.doi.org/10.1186/ar629 - please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: back pain, epidemiology, genetics
Subjects: R Medicine > RC Internal medicine > RC925 Diseases of the musculoskeletal system
Divisions: Faculty of Medicine and Health Sciences > Institute for Science and Technology in Medicine
Related URLs:
Depositing User: Symplectic
Date Deposited: 29 Jun 2017 12:49
Last Modified: 29 Jun 2017 12:55
URI: https://eprints.keele.ac.uk/id/eprint/3694

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