Tools

Silventoinen, K, Jelenkovic, A, Latvala, A, Sund, R, Yokoyama, Y, Ullemar, V, Almqvist, C, Derom, CA, Vlietinck, RF, Loos, RJF, Kandler, C, Honda, C, Inui, F, Iwatani, Y, Watanabe, M, Rebato, E, Stazi, MA, Fagnani, C, Brescianini, S, Hur, Y-M, Jeong, H-U, Cutler, TL, Hopper, JL, Busjahn, A, Saudino, KJ, Ji, F, Ning, F, Pang, Z, Rose, RJ, Koskenvuo, M, Heikkilä, K, Cozen, W, Hwang, AE, Mack, TM, Siribaddana, SH, Hotopf, M, Sumathipala, A, Rijsdijk, F, Sung, J, Kim, J, Lee, J, Lee, S, Nelson, TL, Whitfield, KE, Tan, Q, Zhang, D, Llewellyn, CH, Fisher, A, Burt, SA, Klump, KL, Knafo-Noam, A, Mankuta, D, Abramson, L, Medland, SE, Martin, NG, Montgomery, GW, Magnusson, PKE, Pedersen, NL, Dahl Aslan, AK, Corley, RP, Huibregtse, BM, Öncel, SY, Aliev, F, Krueger, RF, McGue, M, Pahlen, S, Willemsen, G, Bartels, M, van Beijsterveldt, CEM, Silberg, JL, Eaves, LJ, Maes, HH, Harris, JR, Brandt, I, Nilsen, TS, Rasmussen, F, Tynelius, P, Baker, LA, Tuvblad, C, Ordoñana, JR, Sánchez-Romera, JF, Colodro-Conde, L, Gatz, M, Butler, DA, Lichtenstein, P, Goldberg, JH, Harden, KP, Tucker-Drob, EM, Duncan, GE, Buchwald, D, Tarnoki, AD, Tarnoki, DL, Franz, CE, Kremen, WS, Lyons, MJ, Maia, JA, Freitas, DL, Turkheimer, E, Sørensen, TIA, Boomsma, DI and Kaprio, J (2017) Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts. Twin Research and Human Genetics, 20 (5). 395 -405. ISSN 1839-2628

[thumbnail of Zygosity difference in education first revised version.pdf]
Preview
 Text
Zygosity difference in education first revised version.pdf - Accepted Version
Available under License Creative Commons Attribution Non-commercial.
Download (147kB) | Preview
[thumbnail of Figure 1 (2).pdf]
Preview
 Text
Figure 1 (2).pdf - Supplemental Material
Available under License Creative Commons Attribution Non-commercial.
Download (37kB) | Preview
[thumbnail of Supplementary material.pdf]
Preview
 Text
Supplementary material.pdf - Supplemental Material
Available under License Creative Commons Attribution Non-commercial.
Download (325kB) | Preview

Abstract

Whether monozygotic (MZ) and dizygotic (DZ) twins differ from each other in a variety of phenotypes is important for genetic twin modeling and for inferences made from twin studies in general. We analyzed whether there were differences in individual, maternal and paternal education between MZ and DZ twins in a large pooled dataset. Information was gathered on individual education for 218,362 adult twins from 27 twin cohorts (53% females; 39% MZ twins), and on maternal and paternal education for 147,315 and 143,056 twins respectively, from 28 twin cohorts (52% females; 38% MZ twins). Together, we had information on individual or parental education from 42 twin cohorts representing 19 countries. The original education classifications were transformed to education years and analyzed using linear regression models. Overall, MZ males had 0.26 (95% CI [0.21, 0.31]) years and MZ females 0.17 (95% CI [0.12, 0.21]) years longer education than DZ twins. The zygosity difference became smaller in more recent birth cohorts for both males and females. Parental education was somewhat longer for fathers of DZ twins in cohorts born in 1990-1999 (0.16 years, 95% CI [0.08, 0.25]) and 2000 or later (0.11 years, 95% CI [0.00, 0.22]), compared with fathers of MZ twins. The results show that the years of both individual and parental education are largely similar in MZ and DZ twins. We suggest that the socio-economic differences between MZ and DZ twins are so small that inferences based upon genetic modeling of twin data are not affected.

Item Type: Article
Additional Information: This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Cambridge University Press at http://dx.doi.org/10.1017/thg.2017.49 - please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: twins, zygosity, education, parental education
Subjects:


Divisions: Faculty of Medicine and Health Sciences > Primary Care Health Sciences
Related URLs:
Depositing User: Symplectic
Date Deposited: 22 Nov 2017 15:17
Last Modified: 22 Nov 2017 15:18
URI: https://eprints.keele.ac.uk/id/eprint/4264

Actions (login required)

View Item
View Item
Altmetric