Johnson, AE, Sidwick, KL, Pirgozliev, VR, Edge, A and Thompson, DF (2018) The Metabonomic Profiling of Chicken Eggs During Storage Using High Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry. Analytical Chemistry. ISSN 0003-2700

[thumbnail of 30052018_ACS_Manuscript.pdf]
30052018_ACS_Manuscript.pdf - Accepted Version
Available under License Creative Commons Attribution Non-commercial.

Download (733kB) | Preview


Metabonomic techniques have been used to discover subtle differences in the small molecule profiles of chicken
eggs, which could help to combat fraud within the egg industry. High Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry (HPLC-Q-ToF-MS) was used to obtain profiles of the small molecules present in the yolks of chicken eggs stored for different lengths of time. Statistical analysis, including the use of XCMS Online and further exploratory statistics, was able to uncover differences in the abundances of several of the small molecules found in these egg yolks. One of these small molecules was identified, through the use of METLIN and MS/MS analysis, as choline. A targeted study was then carried out over a longer storage period, using the same instrumentation and analytical techniques, in order to observe how the concentration of choline in egg yolk changes over a longer period of time.

Item Type: Article
Additional Information: This is the accepted author manuscript (AAM). The final published version (version of record) is available online via American Chemical Society at - please refer to any applicable terms of use of the publisher.
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Natural Sciences > School of Chemical and Physical Sciences
Related URLs:
Depositing User: Symplectic
Date Deposited: 30 May 2018 10:55
Last Modified: 29 May 2019 01:30

Actions (login required)

View Item
View Item