O'Brien, M, Hall, A, Schrauwen, J and van der Made, J (2018) An open-source approach to automation in organic synthesis: The flow chemical formation of benzamides using an inline liquid-liquid extraction system and a homemade 3-axis autosampling/product-collection device. Tetrahedron. ISSN 0040-4020

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Abstract

Several open-source hardware and software technologies (RAMPS, Python, PySerial, OpenCV) were used to control an automated flow chemical synthesis system. The system was used to effect the synthesis of a series of benzamides. An inexpensive Raspberry Pi single board computer provided an electronic interface between the control computer and the RAMPS motor driver boards.

Item Type: Article
Additional Information: This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Elsevier at https://doi.org/10.1016/j.tet.2018.02.043 Please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: Low-cost-automation; Open-source; Python; OpenCV; Raspberry-Pi; Flow-chemistry; Amide-formation; Liquid-liquid extraction
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Natural Sciences > School of Chemical and Physical Sciences
Depositing User: Symplectic
Date Deposited: 28 Jun 2018 14:07
Last Modified: 18 Mar 2019 11:56
URI: https://eprints.keele.ac.uk/id/eprint/5061

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