Kamyar, N, Greenhalgh, R, Nascimento, T, Medeiros, E, Matthews, PD, Nogueira, L, Haugen, HJ, Lewis, DJ and Blaker, JJ (2018) Exploiting Inherent Instability of 2D Black Phosphorus for Controlled Phosphate Release from Blow-Spun Poly (lactide-co-glycolide) Nanofibers. ACS Applied Nano Materials. ISSN 2574-0970

[thumbnail of ACS-main-final.docx] Text
ACS-main-final.docx - Accepted Version

Download (4MB)


Efforts have been made to stabilize black phosphorus (BP) to utilize its tunable band gap and anisotropic mechanical properties. Here, the intrinsic instability of BP is exploited for controlled therapeutic ion release, namely phosphate. BP was incorporated into degradable poly (lactide-co-glycolide) fibers via solution blow spinning. Raman spectroscopy confirmed the incorporation of 2D-BP into the nanocomposite along with ICP-AES. It was also demonstrated that modifying the initial loading of 2D-BP in the PLGA fibers permitted tunable release rates of phosphate ions over an 8 weeks in vitro study.

Item Type: Article
Additional Information: This is the accepted author manuscript (AAM). The final published version (version of record) is available online via American Chemical Society at http://doi.org/10.1021/acsanm.8b00938 - please refer to any applicable terms of use of the publisher.
Uncontrolled Keywords: black phosphorus, PLGA, solution blow spinning, nanocomposite fibers, phosphate release
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Natural Sciences > School of Chemical and Physical Sciences
Depositing User: Symplectic
Date Deposited: 10 Aug 2018 10:46
Last Modified: 30 Mar 2021 14:06
URI: https://eprints.keele.ac.uk/id/eprint/5210

Actions (login required)

View Item
View Item