Watkinson
Biotin-tagged fluorescent sensor to visualize 'mobile' Zn2+ in cancer cells
Watkinson
Authors
Abstract
A cancer cell-targeting fluorescent sensor has been developed to image mobile Zn2+ by introducing a biotin group. It shows a highly selective response to Zn2+ in vitro, no toxicity in cellulo and images 'mobile' Zn2+ specifically in cancer cells. We believe this probe has the potential to help improve our understanding of the role of Zn2+ in the processes of cancer initiation and development.
Acceptance Date | Jul 27, 2018 |
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Publication Date | Sep 7, 2018 |
Publicly Available Date | Mar 28, 2024 |
Journal | Chemical Communications |
Print ISSN | 1359-7345 |
Publisher | Royal Society of Chemistry |
Pages | 9619-9266 |
DOI | https://doi.org/10.1039/c8cc05425h |
Publisher URL | http://doi.org/10.1039/c8cc05425h |
Files
Acceptedmanuscript.docx
(1.2 Mb)
Document
Publisher Licence URL
https://creativecommons.org/licenses/by-nc/4.0/
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