Edward Roddy e.roddy@keele.ac.uk
Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions for disease elements in gout.
Roddy
Authors
Abstract
OBJECTIVE:
The language currently used to describe gout lacks standardisation. The aim of this project was to develop a consensus statement on the labels and definitions used to describe the basic disease elements of gout.
METHODS: Experts in gout (n=130) were invited to participate in a Delphi exercise and face-to-face consensus meeting to reach consensus on the labelling and definitions for the basic disease elements of gout. Disease elements and labels in current use were derived from a content analysis of the contemporary medical literature, and the results of this analysis were used for item selection in the Delphi exercise and face-to-face consensus meeting.
RESULTS:
There were 51 respondents to the Delphi exercise and 30 attendees at the face-to-face meeting. Consensus agreement (=80%) was achieved for the labels of eight disease elements through the Delphi exercise; the remaining three labels reached consensus agreement through the face-to-face consensus meeting. The agreed labels were: monosodium urate crystals, urate, hyperuric(a)emia, tophus, subcutaneous tophus, gout flare, intercritical gout, chronic gouty arthritis, imaging evidence of monosodium urate crystal deposition, gouty bone erosion and podagra. The face-to-face meeting achieved consensus agreement for the definitions of all 11 elements and a recommendation that the label 'chronic gout' should not be used.
CONCLUSION:
Consensus agreement was achieved for the labels and definitions of 11 elements representing the fundamental components of gout aetiology, pathophysiology and clinical presentation. The Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) recommends the use of these labels when describing the basic disease elements of gout.
Acceptance Date | May 22, 2018 |
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Publication Date | Mar 1, 2019 |
Publicly Available Date | Mar 29, 2024 |
Journal | Arthritis Care and Research |
Print ISSN | 2151-464X |
Publisher | Wiley |
Pages | 427-434 |
DOI | https://doi.org/10.1002/acr.23607 |
Keywords | gout, nomenclature, terminology, urate |
Publisher URL | https://onlinelibrary.wiley.com/doi/abs/10.1002/acr.23607 |
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