Doshi, S, George, S, Kwok, CS, Merchery, A, Mamas, M, Ludman, P, Townsend, J and Bhabra, M (2018) A feasibility study of transaxillary TAVI with the lotus valve. Catheterization and Cardiovascular Interventions, 92 (3). 542 -549. ISSN 1522-1946

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To assess the feasibility of axillary transcatheter aortic valve implantation (TAVI) using the Lotus valve.

TAVI is used to treat patients with severe aortic stenosis, with transfemoral (TF) access being the safest and most widely used route. In patients unsuitable for this, there are reports that the axillary artery may be safest alternative access route. The Lotus device is a fully retrievable 2nd generation transcatheter heart valve which is licensed for femoral and transaortic access. There are limited data on the suitability of this valve for axillary access.

We assessed the feasibility of transaxillary TAVI with the Lotus valve in patients unsuitable for TF TAVI. Between January and October 2016, we identified 10 patients who underwent transaxillary TAVI with the Lotus valve. This cohort was compared with 347 (85%) patients who underwent TF TAVI, 45 (11%) patients who underwent and trans‐apical or direct‐aortic TAVI and the total group of 16 (4%) patients who underwent axillary TAVI.

Ten patients aged 75 years (69–83) underwent attempted TAVI with the Lotus via axillary access. Device success was 100%. In‐hospital and 30‐day mortality was zero. There were no neurological events, no major vascular complications and no myocardial infarctions. Four of 10 patients required a pacemaker post‐TAVI. No patient was left with moderate or greater aortic regurgitation. Median length of stay was 3 days

TAVI with the Lotus valve is feasible via the axillary artery and appears safe in our small cohort of patients.

Item Type: Article
Additional Information: The final published version of this article is available online at
Uncontrolled Keywords: aortic valve disease; structural heart disease intervention; transcatheter valve intervention
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine and Health Sciences > Primary Care Health Sciences
Depositing User: Symplectic
Date Deposited: 29 Jan 2019 11:32
Last Modified: 07 Mar 2019 15:55

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