Simon Davies s.j.davies@keele.ac.uk
Does alanyl-glutamine supplementation offer potential to improve peritoneal dialysate biocompatibility?
Davies
Authors
Abstract
Peritoneal dialysis technique survival remains challenging due to peritonitis and long-term alterations to peritoneal membrane function and integrity. Up to now, the development of less bio-incompatible dialysis solutions have not had a major impact on these aspects of the therapy. A novel approach, supplementing dialysis solutions with a cytoprotective additive, alanyl-glutamine, has shown benefits to surrogate biomarkers of cell function in a randomized controlled study.
| Acceptance Date | Nov 19, 2018 |
|---|---|
| Publication Date | Dec 1, 2018 |
| Journal | Kidney International |
| Print ISSN | 0085-2538 |
| Publisher | Elsevier |
| Pages | 1050 -1052 |
| DOI | https://doi.org/10.1016/j.kint.2018.09.012 |
| Keywords | peritonitis, peritoneal dialysis, dialysis |
| Publisher URL | http://doi.org.10.1016/j.kint.2018.09.012 |
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KI-09-18-1286.pdf
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Publisher Licence URL
https://creativecommons.org/licenses/by-nc-nd/4.0/
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