Choudhury, T, Lurz, P, Schäufele, TG, Menezes, MN, Lavi, S, Tzemos, N, Hartung, P, Stiermeier, T, Makino, K, Bertrand, OF, Gilchrist, IC, Mamas, MA and Bagur, R (2019) Radial versus Femoral Approach for Left Ventricular Endomyocardial Biopsy. EuroIntervention, 15 (8). pp. 678-684. ISSN 1969-6213

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AIMS: Left ventricular endomyocardial biopsy (LV-EMB) is mostly performed via the femoral artery. We assessed the feasibility and safety of radial versus femoral access in patients undergoing LV-EMB. METHODS AND RESULTS: 264 patients from four countries undergoing LV-EMB were collected. Clinical, procedural, safety and feasibility data were compared between groups. LV-EMB was successfully performed via radial approach in 129 (99%) of 130 and 134 (100%) patients by femoral access. Patients in the radial group were older (55.7 versus 44.3 years) and more likely to have moderate-severe mitral regurgitation (27.7% versus transfemoral 0%). Sheathless guides were used in 108 (83.1%) radial and 2 (1.5%) femoral patients; the mean guiding catheter size (radial 7.0±1.0-French versus femoral 8.0±0.1-French, P<0.001) was smaller in the radial group. Mild/moderate radial artery spasm occurred in 13 (10.0%) patients and 1 (0.8%) patient required conversion to femoral access due to severe spasm. No access-site related complications were reported in the radial group while 11 (8.2%) patients in the femoral group had access-site hematomas (P=0.001). There were no major complications in either group. CONCLUSIONS: Radial approach for LV-EMB is feasible and safe, with fewer access-site bleeding complications compared to femoral access. These results study support radial approach for LV-EMB.

Item Type: Article
Additional Information: The final version of this accepted manuscript is available online at
Uncontrolled Keywords: radial; cardiology; endomyocardial
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
R Medicine > RC Internal medicine > RC666 Diseases of the circulatory (Cardiovascular) system
Divisions: Faculty of Medicine and Health Sciences > Primary Care Health Sciences
Related URLs:
Depositing User: Symplectic
Date Deposited: 18 Mar 2019 12:14
Last Modified: 12 Feb 2020 01:30

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