Wu, P, Mamas, MA and Gulati, M (2019) Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics. Journal of Women's Health, 28 (8). 1037 - 1050. ISSN 1540-9996

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Globally, cardiovascular disease (CVD) is the most common cause of mortality in women accounting for one in three deaths. There remains an under recognition of CVD as well as a lack of awareness of risk in women. Promotion of CVD prevention is essential, but the current risk assessment tools do not incorporate any sex-specific cardiovascular risk factors. There is increasing recognition of sex-specific risk factors that appear during pregnancy that are associated with CVD. These adverse pregnancy outcomes (APOs) include preeclampsia, gestational hypertension, preterm birth, gestational diabetes, delivery of a small-for-gestational-age infant, miscarriage, and high parity number. Although the underlying biological mechanism for these association remains to be elucidated, current international guidelines are beginning to recommend the inclusion of APOs in the assessment of CVD risk in women. This review summarizes the evidence for the association between APOs and future CVD. It also highlights the importance of considering APOs in the cardiovascular risk assessment, specifically in young women, allowing for targeted lifestyle-modifying interventions with the potential to alter their risk trajectory and improve their long-term cardiovascular health.

Item Type: Article
Additional Information: The final accepted manuscript and all relevant information regarding this article can be found at; https://www.liebertpub.com/doi/10.1089/jwh.2018.7480
Uncontrolled Keywords: cardiovascular disease, pregnancy, gestational hypertension, preterm birth, gestational diabetes
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RJ Pediatrics
Divisions: Faculty of Medicine and Health Sciences > School of Primary, Community and Social Care
Related URLs:
Depositing User: Symplectic
Date Deposited: 08 Jun 2020 15:31
Last Modified: 13 Aug 2020 01:30
URI: https://eprints.keele.ac.uk/id/eprint/8038

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