Danielle Van Der Windt d.van.der.windt@keele.ac.uk
Moderators of the effects of exercise for hip and knee osteoarthritis: a systematic review of subgroup analyses from randomised controlled trials
Van Der Windt; Healey; Holden
Authors
Emma Healey e.healey@keele.ac.uk
Melanie Holden m.holden@keele.ac.uk
Abstract
Meta-analyses of randomised controlled trials (RCTs) of exercise interventions in people with knee and hip osteoarthritis (OA) provide strong evidence of, on average, a small-to-medium effect on pain and function outcomes compared to comparison interventions/controls. However, not everyone responds to exercise and sub-groups may exist who respond differently. Baseline variables within trials that alter the effect of an intervention are known as moderators. Aims: 1) to identify potential moderators of the effect of exercise explored or tested in RCTs of exercise for knee and hip OA; 2) summarise the evidence reported for these moderators.
| Acceptance Date | Apr 1, 2020 |
|---|---|
| Publication Date | Apr 20, 2020 |
| Journal | Osteoarthritis and Cartilage |
| Print ISSN | 1063-4584 |
| Publisher | Elsevier |
| DOI | https://doi.org/10.1016/j.joca.2020.02.263 |
| Publisher URL | https://doi.org/10.1016/j.joca.2020.02.263 |
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